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A Study to evaluate the effect of an ayurvedic treatment in the cases of chronic kidney disease

Phase 2
Conditions
Health Condition 1: N183- Chronic kidney disease, stage 3 (moderate)
Registration Number
CTRI/2022/09/045326
Lead Sponsor
State Ayurvedic College And Hospital Lucknow
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. History of reduction of kidney function must be present over 3 months.

2. Serum Creatinine level above 1.4 mg/dl and below 4.6 mg/dl

3. Serum Urea level above 40mg/dl and below101mg/dl

4. Patient having Hb level >8gm/dl

5. GFR 30- 90ml/min/1.73m2

6. BUN [Blood urea Nitrogen] above 18.6mg/dl and below 46.8mg/dl

Exclusion Criteria

Age below 35 and above 65 years.

Blood Urea more than 100mg/dl and below 41mg/dl

Serum creatinine level above 4.5 mg/dl and below 1.5mg/dl

BUN [Blood urea Nitrogen] above 46.7mg/dl and below 18.7mg/dl

GFR < 30ml/min/1.73m2

Patients under frequent dialysis

Uncontrolled Diabetes mellitus

Malignant Hypertension

Grade III Prostate

Prostate Carcinoma

Tubercular Nephritis

Hypovolemia

Liver Failure

Heart Failure

Acute Myocardial Infarction

Sever Valvular Disease

Tense Ascites

Sepsis

Haemorrhage

Pancreatitis

Renal artery/ vein obstruction

Microangiopathies like DIC, TTP

Systemic Disease like lupus, lymphoma, Leukaemia, sarcoidosis

Congenital Disease of kidney ex- Polycystic kidney disease

Transplant allograft failure

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1. Blood Urea <br/ ><br>2. Serum Creatinine <br/ ><br>3. GFR (Glomerular filtration rate) <br/ ><br>4. Blood Urea NitrogenTimepoint: Before trial, 4 week, 8 week, 12th week, after trial
Secondary Outcome Measures
NameTimeMethod
�म�त�रावर�ध <br/ ><br>�म�त�र������र�ता <br/ ><br>�म�त�राल�पता <br/ ><br>�म�त�रदाह <br/ ><br>�Anorexia <br/ ><br>�Vomiting <br/ ><br>�Pruritis <br/ ><br>�Oedema <br/ ><br>�Nocturia <br/ ><br>�Thirst <br/ ><br>�Dozing & Sleeplessness <br/ ><br>�Dyspnoea <br/ ><br>�Anaemia <br/ ><br>Timepoint: Before Trial, 15day, 30 day. 45 day, 60 day, 75 day, 90 day, after trial;Urine Routine and Microscopy <br/ ><br>Blood sugar (FBS,PP) <br/ ><br>Renal Function Test <br/ ><br>Liver Function Test <br/ ><br>Timepoint: Before Trial,30 day. 60 day, 90 day, after trial
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