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Clinical Trials/NCT03979794
NCT03979794
Terminated
Not Applicable

A Distress Screening and Intervention in Cancer Surgery

Baylor College of Medicine1 site in 1 country16 target enrollmentDecember 17, 2020
ConditionsCancerStress

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cancer
Sponsor
Baylor College of Medicine
Enrollment
16
Locations
1
Primary Endpoint
Patient Health Questionnaire-8
Status
Terminated
Last Updated
last year

Overview

Brief Summary

The goal of this project is to examine initial effectiveness of a brief (2 preoperative, 2 postoperative session) cognitive behaviorally-based telephone intervention compared to standard care on postoperative outcomes for patients who are scheduled to undergo a cancer-related surgery in 12 or more days and screen positive for distress (4 or higher on 0-10 Distress Thermometer). The intervention focuses on improving emotional and physical health through relaxation, behavioral activation, increased physical activity, and adherence to medication and wound care. Participants will be randomly assigned to receive the intervention or to receive standard care. Outcomes assessed 4 and 6 weeks post-operatively will include: Depression (Patient Health Questionnaire-8), anxiety (Generalized Anxiety Disorder-7), health-related QOL (SF-36 MCS and PCS), number and type of complications, length of stay, and 30-day readmission.

Registry
clinicaltrials.gov
Start Date
December 17, 2020
End Date
November 12, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Chelsea Ratcliff

Adjunct Assistant Professor

Baylor College of Medicine

Eligibility Criteria

Inclusion Criteria

  • ADULT (18 years of age or older)
  • SCHEDULED FOR SURGERY FOR CANCER (excluding non-melanoma skin cancer) 12 OR MORE DAYS IN ADVANCE OF CONSENT
  • SIGNIFICANTLY DISTRESSED (\>4 on the 0-10 Distress Thermometer)
  • ABLE TO SPEAK ENGLISH

Exclusion Criteria

  • COGNITIVE IMPAIRMENT : \<4 on baseline Mini Cog measure
  • SERIOUS MENTAL ILLNESS: a diagnosis of a bipolar or psychotic disorder (noted in medical record)
  • NON-ENGLISH SPEAKING: This study only involves participants who can speak English.

Outcomes

Primary Outcomes

Patient Health Questionnaire-8

Time Frame: 4-weeks post-operation (+/-1 week)

PHQ-8 assesses depression symptoms; A total score (range: 0-24) will be used with higher scores representing more depressive symptoms.

Generalized Anxiety Disorder-7

Time Frame: 4-weeks post-operation (+/-1 week)

The GAD-7 measures anxiety symptoms; A total score (range: 0-21) will be used with higher scores representing more anxiety symptoms.

Secondary Outcomes

  • Hospital Readmission(30 days post-operation)
  • Number of Complications(30 days post-operation)
  • Medical Outcomes Study Short Form-36 (SF-36) Physical Health Component Scale (PCS)(4-weeks post-operation (+/-1 week))
  • Length of post-operative hospital stay(30 days post-operation)
  • Medical Outcomes Study Short Form-36 (SF-36) Mental Health Component Scale (MCS)(4-weeks post-operation (+/-1 week))

Study Sites (1)

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