Serum Hs-CRP in Periodontitis Patients With or Without Diabetes

Not Applicable

Completed

• Conditions: Periodontal Disease; Diabetes Mellitus, Type 2

• Registration Number: NCT03908606
• Lead Sponsor: Cairo University

Brief Summary

the aim of this study was to assess serum levels of high sensitivity c reactive protein in periodontitis patients with and without type 2 diabetes in a trial to analyze its prognostic effect following non-surgical periodontal therapy.

Detailed Description

Periodontitis and diabetes are chronic disorders with a two-way correlation as they can both stimulate an inflammatory response with subsequent formation of inflammatory mediators and cytokines. C reactive protein is an inflammatory plasma marker having a role in the systemic reaction to inflammation. thus, our aim in the current study was to evaluate serum levels of high sensitivity c reactive protein in periodontitis patients with and without type 2 diabetes in a trial to analyze its prognostic effect following non-surgical periodontal therapy. A total of 60 patients were enrolled in this study. ELISA was used for determination of hs- CRP. Non- surgical periodontal therapy was carried out for all periodontitis patients.

Study Timeline

• Study Start: 2018-04-11
• Primary Completion: 2019-01-02
• Study Completion: 2019-01-02
• Status Verified: 2019-04
• Study First Submitted: 2019-04-06
• Study First Submitted QC: 2019-04-08
• Last Update Submitted: 2019-04-08
• Study First Posted: 2019-04-09
• Last Update Posted: 2019-04-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Diabetic patients type 2
2. Periodontitis patients

Exclusion Criteria

1. Smokers
2. Pregnant females

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
clinical attachment level	3 months	gain in clinical attachment level

Trial Locations

Locations (1)

Cairo University; 🇪🇬 Cairo, Egypt