Adjuvant Low Dose Total Body Irradiation in Elderly Patients With Diffuse Large B-Cell Lymphoma

Phase 2

Completed

• Conditions: Non Hodgkin's Lymphoma

• Registration Number: NCT00834951
• Lead Sponsor: University of Aarhus

Brief Summary

The purpose of this study is to determine whether the application of low dose total body irradiation following chemo-immuntherapy in elderly patients with aggressive with non-Hodgkin's lymphoma would be safe and potentially benecicial adjuvant therapy

Detailed Description

Not available

Study Timeline

• Study Start: 2003-01
• Primary Completion: 2007-12
• Study Completion: 2008-12
• Status Verified: 2009-02
• Study First Submitted: 2009-02-02
• Study First Submitted QC: 2009-02-02
• Last Update Submitted: 2009-02-02
• Study First Posted: 2009-02-03
• Last Update Posted: 2009-02-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• previously untreated, pathology verified aggressive non-Hodgkin lymphoma of the diffuse large B-cell type according to the WHO classification. Age between 60 years and 80 years.Positive for an anti-CD20 antibody. Good performance status and normal initial normal blood count.

Exclusion Criteria

• Patients with previous lymphoma associated with immune suppression of any sort. Diagnosis or history of indolent lymphoma or other malignancies. Marked impairment of any vital organ such as the heart, lung, liver or kidneys.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP