Relationship Between Muscle Strength and Physical Function in ICU

Completed

• Conditions: Critical Illness; Physical Dependence; Muscle Weakness; Physical Disability

• Registration Number: NCT04284475
• Lead Sponsor: University of Liege

Brief Summary

This observational study aims to assess the relationship between muscle strength and physical function in critical ill patients. Grip and quadriceps strengths are measured using a standardized protocol of dynamometry. Physical function is assessed using the validated ICU mobility scale.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-10-01
• Primary Completion: 2019-12-31
• Study First Submitted: 2020-02-18
• Study First Submitted QC: 2020-02-22
• Study First Posted: 2020-02-25
• Status Verified: 2021-11
• Study Completion: 2021-11-01
• Last Update Submitted: 2021-11-23
• Last Update Posted: 2021-11-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 93

Inclusion Criteria

• ICU stay of at least 48h
• Collaborative (RASS score -1 to +1)

Exclusion Criteria

• Refusal
• Coma
• Non collaborative
• Hemi / tetra paresis or plegia

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quadriceps strength	as soon as collaborative during ICU stay and up to 1 month following ICU discharge	Quadriceps maximal isometric strength measured using dynamometry
Handgrip strength	as soon as collaborative during ICU stay and up to 1 month following ICU discharge	Grip maximal isometric strength measured using dynamometry
ICU mobility scale	as soon as collaborative during ICU stay and up to 1 month following ICU discharge	Ranking the patient on the scale according to his/her physical capacity. ICU mobility scale is a 10 points scale: 0 means the patient is lying in bed, 10 means the patient is able to walk independently

Trial Locations

Locations (1)

University Hospital of Liège; 🇧🇪 Liège, Belgium