PENG vs FICB for Hip Fracture in ED Patients

Not Applicable

Recruiting

• Conditions: Femoral Neck Fractures; Intertrochanteric Fractures
• Interventions: Procedure: PENG; Procedure: FICB

• Registration Number: NCT05505604
• Lead Sponsor: University of Virginia

Brief Summary

Regional anesthesia for hip fractures has been shown to decrease rates of delirium in elderly patients with hip fractures as well as improve pain compared to systemic opioids. The Pericapsular Nerve Group (PENG) block has recently received attention as an alternative approach to femoral nerve block and Fascia Iliaca Compartment Block (FICB). The investigators seek to evaluate if there is a difference between the PENG and FICB in terms of efficacy of pain control in ED patients presenting with hip fracture. We hypothesize that the PENG block may be superior based on previous research.

Detailed Description

Fractures of the proximal femur are a common presentation to the emergency department and are an acutely painful condition. This condition predominantly affects elderly patients who are at risk for delirium and more susceptible to the adverse effects of systemic opioids. Regional anesthesia is an recommended component of pain control for elderly patients with hip fracture. The investigators seek to compare the efficacy of pain control of the Pericapsular Nerve Group (PENG) block with the Fascia Iliaca Compartment Block (FICB).

Previous studies have suggested that the PENG block may be superior to the FICB for pain control and results in less thigh motor weakness. The investigators will compare pain control (by difference in mean VAS score at set time points), systemic opioid use (in mean morphine equivalents prior to surgery), and motor function in patients with hip fractures who receive either block in the ED.

Study Timeline

• Study First Submitted: 2022-08-15
• Study First Submitted QC: 2022-08-15
• Study First Posted: 2022-08-18
• Study Start: 2022-09-30
• Status Verified: 2024-06
• Last Update Submitted: 2024-06-12
• Last Update Posted: 2024-06-14
• Primary Completion: 2025-09-30
• Study Completion: 2025-09-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Proximal femur fracture

Exclusion Criteria

• refusal to consent
• hemodynamic instability
• allergy to local anesthetics
• severe injury with instability
• severe medical conditions with instability

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
PENG	PENG	Patients with hip fracture randomized to receive PENG block
FICB	FICB	Patients with hip fracture randomized to received FICB

Primary Outcome Measures

Name	Time	Method
Pain score	6 hours	Median pain score on 0-10 Numeric Rating Scale

Secondary Outcome Measures

Name	Time	Method
Opioid use	From block administration until time of surgery or 24 hours if surgery performed >24 hours	Mean opioid consumption in morphine equivalents

Trial Locations

Locations (1)

University of Virginia Medical Center; 🇺🇸 Charlottesville, Virginia, United States