A study on improvement of skin conditions by the supplementation with lactic acid bacteria
- Conditions
- Healthy subjects
- Registration Number
- JPRN-UMIN000050034
- Lead Sponsor
- Kaneka Corporation
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- 60
Not provided
Subjects who met the following exclusion criteria are excluded from the study: 1) regularly use of medicines or supplements for the skin, or regularly user of probiotics supplements 2) have skin disease symptoms such as atopic dermatitis, or scars/ inflammation at the test sites 3) have severe hay fever / allergic symptoms on face 4) have food allergies 5) have disease such as hepatic, renal, gastrointestinal, cardiac, respiratory, endocrine, or metabolic diseases 6) have a history of cosmetic or medical treatments, hormone replacement therapy within the past 6 months, or intend to undergo such treatments during the study period 7) cannot refrain from undergoing tanning / visiting strong sunlight area during the study period 8) cannot refrain from direct sunlight for sports, etc 9) have digestive diseases / a history of digestive surgery 10) Pregnant, lactating, or intending to become pregnant 11) Drinker (20 g/day or more of pure alcohol for 4 or more days per week), or cannot abstain from alcohol for 2 days prior to each examination. 12) Shift workers, late night workers, or have a plan of travel abroad 13) cannot avoid changing / addition of skin care products 14) cannot avoid shaving the skin for 7 days prior to the date of each examination 15) participated in other studies within 1 month prior to the date of informed consent, or have a plan to participate in other studies during this study. 16) deemed inappropriate by the corresponding investigator with a medical license
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Skin moisture (stratum corneum water content), Trans epidermal water loss, Skin elasticity
- Secondary Outcome Measures
Name Time Method Other skin conditions (melanin content, erythema, texture, wrinkles, spots, etc.), Stratum corneum analyses, Questionnaire for skin and mental conditions, Izumo scale score, Physical parameters, Hematology parameters, Blood chemical/biochemical parameters, Urine biochemical parameters