跳至主要内容
临床试验/NCT07241507
NCT07241507已完成不适用

Frequency of Wound Dehiscence and Wound Infection in Continuous Versus Interrupted Suturing for Abdominal Closure in Exploratory Laparotomy

Allama Iqbal Teaching Hospital2 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2024年9月11日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
80
试验地点
2
主要终点
Wound Dehiscence

研究概览

简要总结

The goal of this clinical trial is to learn whether the type of suturing technique used to close the abdomen after exploratory laparotomy affects the rate of wound complications. Specifically, the study aims to find out if using interrupted sutures results in fewer cases of wound dehiscence (wound reopening) compared to continuous sutures.

The main question the study seeks to answer is:

Does interrupted suturing reduce the frequency of wound dehiscence compared to continuous suturing in patients undergoing exploratory laparotomy?

Researchers will also observe and compare wound infection rates between the two suturing methods.

About 80 adult patients (18-60 years old) undergoing exploratory laparotomy at the Department of General Surgery, DHQ Teaching Hospital, Dera Ghazi Khan, will take part in this study. Participants will be randomly assigned to one of two groups:

Group A: Continuous abdominal closure using No. 1 Vicryl suture

Group B: Interrupted abdominal closure using No. 1 Vicryl suture

All participants will have their baseline characteristics recorded, including age, gender, obesity, diabetes, and smoking status. The surgical technique and postoperative care will follow the hospital's standard protocols. After surgery, patients will be followed for four weeks with weekly clinical assessments to check for wound infection or wound dehiscence.

The hypothesis is that patients whose abdominal wounds are closed with interrupted sutures will have a lower frequency of wound dehiscence compared to those with continuous sutures.

The findings will help guide surgeons on which abdominal closure method provides better wound healing and fewer postoperative complications.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Undergoing exploratory laparotomy
  • Both emergency and elective

排除标准

  • Patients undergoing second laparotomy or re- laparotomy
  • Patients on steroid therapy (assessed on medical record review)
  • Patients who die within 28-days of surgery

结局指标

主要结局

Wound Dehiscence

时间窗: From enrollment to 28-days of operation

A partial or total separation of previously approximated wound edges, on clinical examination of surgical wound.

次要结局

未报告次要终点

研究者

发起方
Allama Iqbal Teaching Hospital
申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Muhammad Shehroz Sarwar

Principal Investigator

Allama Iqbal Teaching Hospital

研究点 (2)

Loading locations...

相似试验