Screening of Helicobacter Pylori in Children of Positive Infected Mothers

• Conditions: H Pylori Infection

• Registration Number: NCT03911791
• Lead Sponsor: Assiut University

Brief Summary

Helicobacter pylori is aspiral shaped gram negative organism that colonized the gastric mucosa.it was showen that intra familial infection play role in transmission of H pylori and mother play the key role in transmission .

Detailed Description

Prevelance of H pylori infection in children whose mother positive infected is different according to risks factors such as mother education,work out side or not , socioeconomic status, family size and breast feeding or not.H pylori in children can be represent with recurrent abdominal pain ,recurrent diarrhea,repeated vomitting ,pallor ,fulness,non variceal hematemesis,loss of appetite,reterded growth.complication of H pylori include gastric ulcer,duodenal ulcer,gastric atrophy may lead to gastric cancer and intestinal metaplasia.

Study Timeline

• Status Verified: 2019-03
• Study First Submitted: 2019-03-10
• Study First Submitted QC: 2019-04-09
• Last Update Submitted: 2019-04-09
• Study First Posted: 2019-04-11
• Last Update Posted: 2019-04-11
• Study Start: 2020-04-01
• Primary Completion: 2020-04-01
• Study Completion: 2021-04-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Child with Dyspeptic symptoms

Exclusion Criteria

malnutrition childs Patient with metabolic disorder

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess prevelance of H pylori infection in children born of infected positive mother	Period from April 2019 to April 2020	By taken children whose mother infected ,how many of them infected by this microbe by taken these child and done the following investigastion as stool antigen test and biobsy if they are postive by test and then follow up by treatment
Asse the effect of Helicobacter pylori infection in children with anemia	Period from April 2019 to April 2020	By knowing effect of this microbe on growth development of children by measure weigt /height through body mass index and measure heamoglbin level; By taken children whose positive H pylori follow effect of this microbe on heamoglbin level and do investigation as complete blood count By following test such as complete blood count and heamoglbin level and if this microbe increase level of anemia or not