Effects of single Platelet-Rich Plasma local injection on pain, symptom severity, functional state and electrodiagnostic findings in women with mild and moderate Carpal Tunnel Syndrome, A clinical trial

Vice chancellor for research,Shahid Beheshti University of Medical Sciences0 个研究点目标入组 41 人开始时间: 待定最近更新: 2018年2月22日

适应症

试验速览

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•patient with mild and moderate CTS confirmed by the presence of one or more of the following standard electrophysiological criteria: 1- prolonged distal motor latency (DML) (abnormal response is more than 4.2 millisecond) of Median nerve and 2- prolonged antidromic distal sensory latency (DSL) to the third digit (abnormal response is more than 3.6 millisecond); Exclusion criteria: Pregnancy; Severe degree CTS; Background metabolic diseases such as: diabetes mellitus; hypothyroidism; rheumatoid arthritis; Previous history of corticosteroid injection in Carpal Tunnel Syndrome; Severe atrophy of thenar muscles; cervical radiculopathy or significant polyneuropathy; Unwillingness to participate in the present study; patient younger than 20 or older than 65 years old; history or presence of cancer or malignant disorders; presence of immunosuppressive, autoimmune and platelet disorders; treatment with anticoagulant and anti-platelet medications 10 days before injection; use of NSAIDs 2 days before injection; use of systemic corticosteroids 2 weeks before PRP injections; hemoglobin measures of less than 12 g/dl and platelet counts of less than 150,000 per micro liter

发起方

Vice chancellor for research,Shahid Beheshti University of Medical Sciences