Non-prescription Versus Prescription Topical Treatments Versus no Treatment in the Control of Sweating

Not Applicable

Completed

• Conditions: Hyperhidrosis; Excess Sweating
• Interventions: Drug: Drysol; Drug: Drioff

• Registration Number: NCT00509886
• Lead Sponsor: Northwestern University

Brief Summary

The purpose of this study is to assess the effectiveness of the prescription treatment compared to the non-prescription treatment. It is hypothesized that the prescription treatment will have a significantly greater effect than the non-prescription treatment on decreasing excess sweating.

Detailed Description

The objective of this study is to assess the effectiveness of the prescription treatment compared to the non-prescription treatment. It is hypothesized that the prescription treatment will have a significantly greater effect than the non-prescription treatment on decreasing excess sweating.

Study Timeline

• Study Start: 2007-06
• Study First Submitted: 2007-07-31
• Study First Submitted QC: 2007-07-31
• Primary Completion: 2007-08
• Study Completion: 2007-08
• Study First Posted: 2007-08-01
• Status Verified: 2014-11
• Last Update Submitted: 2014-11-07
• Last Update Posted: 2014-11-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• age 21-30 years
• males and females
• The subjects are in good health.
• The subjects have willingness and the ability to understand and provide informed consent for participation in the study.

Exclusion Criteria

• Subjects with primary hyperhidrosis
• Subjects who are unable to withstand prolonged heat exposure or who have self-reported history of cardiovascular or respiratory disorders.
• Subjects who are unable to give informed consent.
• Subjects with mental illness.
• Subjects who are pregnant or nursing.
• Subjects with systemic or local skin disease and/or infection that may interfere with the conduct of the study.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
1	Drysol	ARMs were randomized. One side of the body received treatment with one antiperspirant and the contralateral side with a different antiperspirant.
2	Drioff	ARMs were randomized. One side of the body received treatment with one antiperspirant and the contralateral side with a different antiperspirant.

Primary Outcome Measures

Name	Time	Method
Gravimetric analysis	3 hours

Secondary Outcome Measures

Name	Time	Method
HDSS	3 hours
Subject sweat assessment	3 hours

Trial Locations

Locations (1)

Northwestern University Dermatology; 🇺🇸 Chicago, Illinois, United States