Physiological Brain Atlas Development
- Conditions
- Parkinson DiseaseObsessive Compulsive DisorderDepressionDystoniaTremors
- Registration Number
- NCT01210534
- Lead Sponsor
- Ohio State University
- Brief Summary
Enrollment of candidates undergoing a deep brain stimulator (DBS) implant.
- Detailed Description
The study proposes the enrollment of candidates undergoing a deep brain stimulator (DBS) implant. Data will be collected before, during and after surgery and will be electronically entered into the Atlas database where it will be stored indefinitely.
The purpose of the study is to create an Atlas to store physiological information utilizing non-rigid MRI normalization algorithms. In addition to collating and analyzing the physiological atlas in a statistical manner that allows the surgeon to predict optimal targeting locations for DBS implants based on multiple physiological variables, including pre-operative severity of disease, intraoperative neurophysiological observations, and post-operative response to DBS stimulation therapy.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 456
- Any patient between the age of 7-90
- Patients who have undergone deep brain stimulation (DBS) surgery as standard of care at The Ohio State University
- None
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method optimal DBS target location intra-operative identification To create an atlas that will allow physiological information to be assigned to anatomical locations in MRI space, utilizing non-rigid MRI normalization algorithms.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
The Ohio Sate University
🇺🇸Columbus, Ohio, United States