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Clinical Trials/NCT01774240
NCT01774240
Completed
Not Applicable

Incidence, Severity and Treatment of Delirium in Cardiac Surgery Patients: A Before-after Study

Rigshospitalet, Denmark1 site in 1 country230 target enrollmentApril 2012
ConditionsDelirium

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Delirium
Sponsor
Rigshospitalet, Denmark
Enrollment
230
Locations
1
Primary Endpoint
number of delirium free days
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Delirium is a common yet under diagnosed condition in hospitalized patients, and the incidence have not previously been described in Danish cardiac surgery patients. The present study seeks to describe the incidence and duration of delirium in this group of patients, before and after the introduction of standardized screening tool and a guideline for treatment of delirium after cardiac surgery.

Detailed Description

Delirium is a common yet under diagnosed condition in cardiac surgery patients, and may cause prolonged cognitive impairment and increased risk of complications. Patients are at risk of e.g. pulling catheters and lines and may fall attempting to get out of bed. The aging patient population present with many risk factors for developing delirium, but diagnostic tools have been few. Almost 50% present with hypoactive delirium, which is often not diagnosed, nor treated correctly. To optimize effect, treatment should be initiated early, maintained until clinical improvement is observed, and then tapered gradually. Recently, Delirium Observation Screening scale (DOS scale) was developed and validated in elective cardiac surgery patients in the Netherlands, with interesting results. This encouraged us to evaluate the effects of systematic delirium screening and treatment in cardiac surgery patients. To our knowledge, no prior studies have evaluated use of DOS scale in this context. OBJECTIVES To evaluate the incidence and severity of delirium, and the effects of standardized treatment in a population of Danish cardiac surgery patients.

Registry
clinicaltrials.gov
Start Date
April 2012
End Date
December 2012
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Vibeke Lind Jørgensen

MD, PhD, resident

Rigshospitalet, Denmark

Eligibility Criteria

Inclusion Criteria

  • adult patients admitted for cardiac surgery at department of cardiothoracic surgery, Rigshospitalet, denmark

Exclusion Criteria

  • patients under age 18,
  • patients that died within 24 hours after admission.

Outcomes

Primary Outcomes

number of delirium free days

Time Frame: 14 days

number of delirium free days are calculated as percentage of length of stay (LOS) in days. Participants will be followed for the duration of hospital stay, an expected average of 2 weeks

Secondary Outcomes

  • complication rates(14 days)

Study Sites (1)

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