The effect of continuation of anti-platelet agents on bleeding complications after dento-alveolar surgical procedures
Completed
- Conditions
- Parodontitis apicalis, adult parodontitis, cariesOral Health1. Diseases of pulp and periapical tissues 2. Gingivitis and periodontal diseases 3. Dental caries
- Registration Number
- ISRCTN54741248
- Lead Sponsor
- Academic Medical Centre (AMC) (Netherlands)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 145
Inclusion Criteria
1. Patient on antiplatelet therapy who has to be treated in the AMC at the Department of Oral and Maxillofacial surgery
2. Approval of the prescribing physician
3. At least 18 years old
Exclusion Criteria
1. Known coagulation defect
2. Use of oral anticoagulant treatment (vitamin K antagonists) or therapeutic heparin
3. Severe kidney dysfunction (creatinine clearance <20 ml/min) or hepatic dysfunction
4. Unstable coronary artery disease
5. Patients younger than 18 years of age
6. Refusal to provide informed consent
7. Recent placement of a coronary stent (during the last 6 months)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Peri-procedural blood loss
- Secondary Outcome Measures
Name Time Method 1. Occurrence of thrombo-embolic events at 30 days follow-up<br>2. The predictive effect of measurements in DNA, blood and saliva on peri-procedural hemostasis and blood loss