Post -transplantation Cyclophosphamide as Graft Versus Host Disease prophylaxis in Children with ß-Thalassemia Major undergoing Hematopoietic Stem Cell Transplantatio
- Conditions
- Haematological DisordersPaediatrics
- Registration Number
- PACTR202311877246623
- Lead Sponsor
- faculty of medicine tanta university
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Children with ß-thalassemia major (Pesaro class I, II) undergoing allogeneic peripheral blood stem cell transplantation from matched related donor aged 2- 18 years.
i.Children with ß-thalassemia major (Pesaro class III).
ii.Conditions with contraindication to cyclophosphamide use as ( systemic infections , uric acid kidney stones , inflammation of bladder with hemorrhage , obstruction of any part of the urinary tract , bloody urine , kidney disease with likely reduction in kidney function , children with a previous hypersensitivity to it .
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.