Surgical Outcomes of Vitrectomy for Epiretinal Membrane with Good Visual Acuity-better than 0.9 decimal visual acuity
- Conditions
- Epiretinal membrane
- Registration Number
- JPRN-UMIN000021220
- Lead Sponsor
- ihon University hospital
- Brief Summary
[Purpose] To evaluate the efficacy of epiretinal membrane removal in patients with good visual acuity for improving visual function and quality of life (QOL). [Subjects and Methods] A prospective case study. 37 subjects with good visual acuity better than 0.9 (good group) was compared to 35 patients with visual acuity of 0.3 to 0.8 (moderate group) in 3-and 6-month data. Linear mixed-effect models were used for statistical analysis. The primary outcome was 6 months postoperative horizontal metamorphopsia (MH). Secondary outcomes are postoperative visual acuity, 1,3,6-months postoperative MH, vertical metamorphopsia (MV), aniseikonia, streopsis, and central foveal thickness. In the good group, QOL assessment using NEI VFQ 25 at 6 and 12 months was examined. [Results] In good group, MH was improved significantly from 0.84 to 0.44 degree at 3 months, 0.45 degree at 6 months and 0.36 degree at 12 months after surgery (P<0.0001, respectively), however there was no significant difference from the moderate VA group. There was no improvement in MV score at the final observation in both groups. LogMAR VA significantly improved from -0.09 preoperatively to -0.046 at 12 months in good group and was significantly better than moderate group. Preoperative vertical and horizontal aniseikonia score remained unchanged in good group at 6 months (P = 0.75, 0.71), while in moderate group, both vertical and horizontal aniseikonia score worsened(P = 0.01, 0.01). The NEI VFQ-25 score improved in good VA group by general health, general vision, mental health.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Not provided
1 Eyes performed vitrectomy before 2 Eyes which have other diseases such as inflammatory or vascular diseases
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The horizontal metamorphopsia at 6 months after surgery
- Secondary Outcome Measures
Name Time Method Visual acuity, The horizontal metamorphopsia at 1,3,12 months after surgery, The vertical metamorphopsia at 1,3,6,12 months after surgery, The streopsis at 1,3,6,12 months after surgery, Central foveal thickness and continuity of IS/OS line, Reading score, National Eye Institute Visual Function Questionnaire 25 (NEI VFQ-25), Pathological findings