Cryotherapy for Neuropathy in Children

Not Applicable

• Conditions: Cancer
• Interventions: Other: Cryotherapy (apparatus)

• Registration Number: NCT04536207
• Lead Sponsor: South Valley University

Brief Summary

This study aimed to assess the efficacy of cryotherapy in controlling Peripheral Neuropathy in cancer children

Detailed Description

Peripheral neuropathy is a serious condition characterized by symmetrical, distal damage to the peripheral nerves that may be caused by several classes of drugs, including chemotherapeutic agents. Chemotherapy-induced peripheral neuropathy (CIPN) is an adverse effect estimated to occur in up to 40% of patients undergoing chemotherapy, with its incidence increasing in patients being treated with multiple agents. Pharmacists play a pivotal role in the prevention and management of CIPN by recommending evidence-based pharmacologic and non pharmacologic strategies appropriate for the individual patient.Peripheral neuropathy (PN) is a systemic disease characterized by symmetrical, distal damage to the peripheral nerves that negatively impacts patient quality of life (QOL). Prolonged symptoms associated with PN can cause pain, interfere with functional ability (e.g., dressing, driving, house-work), and disrupt emotional health.

Study Timeline

• Study First Submitted: 2020-08-16
• Study First Submitted QC: 2020-08-29
• Study First Posted: 2020-09-02
• Status Verified: 2021-10
• Last Update Submitted: 2021-10-13
• Last Update Posted: 2021-10-15
• Study Start: 2022-02-01
• Primary Completion: 2022-06-30
• Study Completion: 2022-07-15

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Their age will ranging from eight to seventeen years.
2. Children participated in this study will from both sexes.
3. Children receiving chemotherapy as medical treatment protocol
4. All children have polyneuropathy caused by chemotherapy.

Exclusion Criteria

1. Children with Epilepsy.
2. Children with blood clotting disorder.
3. Children have Open wounds / broken skin
4. Children with severe cardiac disease
5. Uncooperative patients.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
the study group	Cryotherapy (apparatus)	Group (A) the study group received cryotherapy

Primary Outcome Measures

Name	Time	Method
Nerve conduction studies (NCS)	nerve conduction velocity for motor common peroneal nerve at day 90	nerve conduction velocity for motor common peroneal nerve

Trial Locations

Locations (1)

South Valley University, Faculty of Physical Therapy; 🇪🇬 Qina,, Egypt