A comparison of the effects of Triamcinolone and Dexmedetomidine in caudal neuroplasty in chronic low back pain.
- Conditions
- low back pain.Low back pain
- Registration Number
- IRCT20111102007984N28
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
1) Chronic low back pain more than six months +/- radiculopathy, 2) Moderate to severe pain score (> 3, based on the Visual Analog Scale),3) Age 40-70 years,4) Inadequate response to conservative and physiotherapy treatments after three months,5) ASA classification I-II,6) Disc protrusion (at MRI)
1) Severe canal stenosis (more than two thirds in axial MRI view), 2) Sequestrated disc (fragmented),3) Decreased disc height more than 60%,4) Sever spinal deformity,5) Spinal tumors,6) Vertebral fracture,7) Spondylolisthesis > Grade II, 8) Local or systemic infection, 9) Taking anticoagulants,10) Drug abuse,11) History of drug reaction,12) Sever psychological disorders,13) Pregnancy and lactation,14) Severe or sudden neurological deficit such as urinary or fecal incontinence,15) Body Mass Index (BMI) > 35,16) Patient's refusal,17) Diabetes mellitus, 18) MRI contraindications (cardiac pacemaker, defibrillator, aortic aneurysm clips),19)Impossible prone positioning
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ow back pain. Timepoint: Before injection,two weeks,1,3 and 6 month after intervention. Method of measurement: pain score measured with visual analogue scale in Questionnaire.
- Secondary Outcome Measures
Name Time Method Oswestry Disability Index questionnaire (ODI) and straight leg raising test (SLR), Reverse straight leg raising test (RSLR),Bonnet,FABER,Gaenslen,Tiptoe and Heel walking,analgesic consumption,blood sugar,HbA1C,MRI. Timepoint: Before injection, two weeks, 1,3 and 6 moth after intervention. Blood sugar ,before injection,2 th day and 2th week after injectionHbA1C, before injection,3 and 6 month after injection MRI, before injection and 6 month after injection. Method of measurement: Questionnaire.