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Clinical Trials/NCT05465395
NCT05465395
Suspended
Not Applicable

Effects of Upper Cervical and Thoracic Chiropractic Adjustments on the Autonomic Nervous System and Perceived Stress Response

Life University1 site in 1 country40 target enrollmentOctober 12, 2021
ConditionsStress

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stress
Sponsor
Life University
Enrollment
40
Locations
1
Primary Endpoint
Galvanic Skin Response
Status
Suspended
Last Updated
3 years ago

Overview

Brief Summary

The proposed study examines the differences in how the ANS responds to cervical adjustments in comparison to thoracic adjustments. This study is the continuation of a previous study titled Perceived stress and patterns of autonomic function: a protocol development study. Autonomic tests such as HRV, GSR, and the stress surveys will be the primary method of measurement. CareTaker and Biopac devices will provide continual data collection of ECG (for HRV analysis) and GSR throughout the exam and adjustment. Participant's subjective stress levels will be measured through the use of stress questionnaires including the National Stressful Events Survey Acute Stress Disorder Short Scale, the Hamilton Anxiety Rating Scale, and the Connor-Davidson Resilience Scale. The objective of the study is to determine if the location of a chiropractic adjustment will affect the autonomic nervous system in such a way that PNS or SNS activation increases or decreases after the adjustment. Further, the study will continue to examine how the chiropractic adjustment affects the subjective stress response.

Registry
clinicaltrials.gov
Start Date
October 12, 2021
End Date
November 1, 2023
Last Updated
3 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Sponsor
Life University
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Over the age of 19
  • In good health
  • Willing to have blood pressure taken
  • Willinig to shave a small area of chest hair for placement of a ECG patch
  • Consent to a physical exam
  • Consent ot chiropractic evaluationa nd 2 adjustments

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Galvanic Skin Response

Time Frame: Through study completion, an average of 1 week

Galvanic Skin response gives a strong measure of Sympathetic response via electrical conductivity of perspiration.

NSESSS

Time Frame: Through study completion, an average of 1 week

Measures PTSD symptoms in people 18 and up.

CD-RISC-25

Time Frame: Through study completion, an average of 1 week

Measure of adaptability

Caretaker Heart Rate Variability

Time Frame: Through study completion, an average of 1 week

HRV allows for an understanding of Autonomic (parasympathetic) function, via measuring the interval of R peaks in QRS complexes.

Hamilton Anxiety Rating Scale

Time Frame: Through study completion, an average of 1 week

Measures the severity of anxiety symptoms

Study Sites (1)

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