IV THROMBOLYSIS(rt PA-Alteplase) AS TREATMEANT IN SEVERE COVID ARDS
Not Applicable
- Conditions
- Health Condition 1: J80- Acute respiratory distress syndromeHealth Condition 2: B972- Coronavirus as the cause of diseases classified elsewhere
- Registration Number
- CTRI/2021/08/035445
- Lead Sponsor
- COLUMBIA ASIA REFERRAL HOSITA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Severe COVID -19 ARDS (pao2:fio2 ratio <100) who are admitted to IC
Exclusion Criteria
Prior intracrainial hemorrhage
Iaschemic stroke within 3 months
Uncontrolled hypertension(BP >180/110)
Major surgery within 3 months prior
Non compressible vascular puncture
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ICU MORTALITYTimepoint: 28 DAY ICU mortality
- Secondary Outcome Measures
Name Time Method ICU length of stay. <br/ ><br>Change in pao2/fio2 P/F ratio. <br/ ><br>Timepoint: BEFORE rt PA <br/ ><br>POST rt PA 24HRS, 48HRS, 1 WEEK, @ discharge