Ultrasound-guided Erector Spinae Block Versus Quadratus Lumborum Block for Postoperative Analgesia in Laparotomies: Randomized Controlled Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Total analgesic consumption
研究概览
简要总结
The study aimed to compare the effect of ESP block and QL block in preventing postoperative pain and decreasing analgesic consumption in patients scheduled for laparotomies.
This prospective randomized controlled study will be done after obtaining ethics committee's permission and written informed consent of the patients 60 adult patients aged 18-60 years scheduled for open laparotomies under general anesthesia will be included in this study.
According to the used technique, the patients will be randomly allocated into 3 parallel equal groups (20 patients in each one).
Group I (ES group): the patients will receive bilateral ESP block. Group II (QL group): the patients will receive bilateral QL block. Group III (control group): the patients will not receive any regional block.
详细描述
Postoperative pain management is one of the most important issues influencing the outcome of surgery. Postoperative pain, especially when poorly controlled, results in harmful acute effects such as adverse physiological responses and chronic effects like delayed long term recovery and chronic pain.the investigators aimed to compare the effect of ESP block and QL block in preventing postoperative pain and decreasing analgesic consumption in patients scheduled for laparotomies.
Primary outcome:
Total analgesic consumption in the first 24hrs postoperative.
Secondary outcomes:
- Time of first analgesic request.
- Visual analogue pain score in the first 24hrs postoperative
- Incidence of any side effects. All patients will be premedicated using midazolam 0.03 mg /kg iv upon arrival to the operating room then standard monitoring which included SPO2, ECG, non-invasive blood pressure monitoring will be applied. All patients will receive the same anesthetic technique. Following anesthesia induction using 1-2 mcg/kg fentanyl, 2- 3 mg/kg propofol, and 0.5 mg/kg atracurium, the patients will be intubated and maintenance of anesthesia will be done by Isoflurane (MAC 1.2) and intermittent doses of atracurium to maintain adequate muscle relaxation. All hemodynamics will be measured before and after induction of general anesthesia and then every 5 min till end of surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged 18-60 years.
- •ASA I-II.
- •Both sexes.
- •Open laparotomies.
排除标准
- •Patient refusal
- •Allergy to local anesthetics
- •BMI >40 kg/m2
- •Bleeding diathesis or history of anticoagulant use.
- •Psychiatric diseases.
- •Infection of the skin at the site of needle punctures area.
结局指标
主要结局
Total analgesic consumption
时间窗: 24 hours
total fentanyl consumption as rescue analgesia
次要结局
- dynamic Visual analogue pain score(24 hours)
- resting Visual analogue pain score(24 hours)
- Time of first analgesic request.(24 hours)
研究者
Shadwa Rabea Mohamed
lecturer
Minia University
