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临床试验/NCT01664702
NCT01664702已完成不适用

Substrate Oxidation in Children in Response to Exercise With High and Low Dairy Intake

University of Kansas1 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2005年1月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
24
试验地点
1
主要终点
24hr fat oxidation

研究概览

简要总结

The investigators propose a randomized trial comparing higher levels of dairy intake compared to lower levels of dairy intake. Participants will be 20 boys and girls, age 10-13, overweight (>85%) who are currently consuming 1 or fewer servings of dairy per day. Each participant will be randomized to either higher or lower levels of dairy intake. A baseline calorimeter stay will determine 24-hour energy needs. Participants will then receive the diet they have been randomized to receive for 6 days and will then have a second calorimeter stay. During this 2nd stay, each participant will continue to receive the diet they were randomized to receive and will achieve a 300 kcal energy deficit through physical activity. The investigators hypothesize that children who receive a 300 kcal energy deficit from the energy expenditure of exercise and receive 3 to 4 servings of dairy products will show greater increases in fat oxidation compared to children who receive a 300 kcal energy expenditure of exercise and receive 1 or fewer servings of dairy products.

详细描述

The study objective was to conduct a randomized clinical trial comparing enhanced levels of dairy consumption to lower levels of dairy consumption during an energy deficit resulting from 300 kcal of exercise. Participants were 24 sedentary and overweight boys, 13-15 years of age and girls, 12 to 14 years of age, and consuming 1 or fewer servings of dairy and less than 600 mg calcium per day at baseline. Participants were randomly assigned to either higher or lower dairy for 6 days and then crossed over to the opposite treatment subsequent to 2 weeks of wash out. The investigators provided all meals and snacks for the participants during the higher and lower dairy conditions. During the wash out period, participants were instructed to consume their normal diet as assessed at baseline which consisted of 1 or fewer servings of dairy and less than 600 mg calcium. Participants stayed in the calorimeter at baseline, day 7, and day 28 (end of study), after crossover. The calorimeter measured substrate oxidation under the condition of a 300 kcal energy deficit due to exercise.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Prevention
盲法
None

入排标准

年龄范围
10 Years 至 13 Years(Child)
性别
All
接受健康志愿者
是

入选标准

  • •Must be overweight
  • •and 10-13 years old
  • •currently consuming 1 or fewer servings of dairy
  • •less than 600 mg calcium per day

排除标准

  • •not meeting the above criteria
  • •must be present for duration of the study

研究组 & 干预措施

Recommended dairy diet

Experimental

Recommended servings of dairy products per day

干预措施: Dairy Products (Dietary Supplement)

Low dairy diet

Experimental

One or fewer dairy servings per day

干预措施: Dairy Servings (Dietary Supplement)

结局指标

主要结局

24hr fat oxidation

时间窗: 24 hrs

Fat oxidation over a 24 hr period will be measured using whole room indirect calorimetry.

次要结局

  • 24hr energy expenditure(baseline, 7 days after each diet)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Joseph Donnelly

Professor

University of Kansas

研究点 (1)

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