Effectiveness of Plantago major L. extract nanoparticle and Thai massage combined with Plantago major L. extract nanoparticle in patients with osteoarthritis knee

Not Applicable

Not yet recruiting

• Conditions: Patients with osteoarthritis knee; Osteoarthritis knee, Thai massage, Plantago major L. extract nanoparticle

• Registration Number: TCTR20180614003
• Lead Sponsor: Mae Fah Luang University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-06-14
• Study Completion: 2018-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 69

Inclusion Criteria

- Age more than 50 years old
- The participants have experienced spontaneous knee pain for longer than 12 weeks
- Knee crepitus found during knee movement
- Knee stiffness are most noticeable when the patient try to get out of bed in the morning
- Good communication and cooperation

Exclusion Criteria

- A history of the following diseases or disorders:
1. Neurological disorder
2. Knee infection
3. Contagious skin disease in the leg
- Leg fracture
- Fever

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain Before and after the first treatment session, 1 day and 3 month after end of the intervention Pain scale (visual analogue scale)

Secondary Outcome Measures

Name	Time	Method
Muscle tension Before and after the first treatment session, 1 day and 3 month after end of the intervention Muscle scale (visual analogue scale),Pressure pain threshold Before and after the first treatment session, 1 day and 3 month after end of the intervention Pressure algometry,Balance Before and after the first treatment session, 1 day and 3 month after end of the intervention Time Up and Go Test,Fear related pain Before and after the first treatment session, 1 day and 3 month after end of the intervention Tampa Scale for Kinesiophobia,Anxiety Before and after the first treatment session, 1 day and 3 month after end of the intervention State anxiety inventory,Muscle activity Before and after the first treatment session, 1 day after end of the intervention Electromyogram (EMG),Patient satisfaction After end of the intervention Patient satisfaction questionnaire