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Prevalence of CVC-associated Sepsis and Use of Blood Cultures in Berlin - Brandenburg

Terminated
Conditions
Bacteremia
Registration Number
NCT01388686
Lead Sponsor
Charite University, Berlin, Germany
Brief Summary

Structured web-based survey in selected hospitals with intensive care units in Berlin- Brandenburg to collect data on the overall number of blood cultures (used) and the prevalence of (positive blood cultures in patients with) CVC - associated sepsis.

Detailed Description

The use of CVC represents one of the major risk factors for sepsis, a highly prevalent disease in ICUs. Blood cultures obtained prior to antibiotic administration are part of the SSC Resuscitation Bundle and essential for the outcome of the patient. The CDC criteria to diagnose sepsis do not take into account the overall number of blood cultures obtained and thus, lead to an underestimation of the true incidence of sepsis. Up to now, few data is available on the total number of blood cultures obtained and the relation to the incidence of sepsis in German ICUs.

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
13
Inclusion Criteria
  • Intensive care units of hospitals in the INABBRA alliance.
  • Patients with bacteremia.
Exclusion Criteria
  • Hospitals without intensive care unit.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Total number of blood cultures drawn and total number of positive findings in ICUs1 year

Retrospective analysis of cases with positive bloodculture among patients in ICU setting compared to the total amount of blood cultures taken in the same period of time and same hospital.

Secondary Outcome Measures
NameTimeMethod
Prevalence on CVC - associated sepsis/CLABSIs1 year

Trial Locations

Locations (1)

Department of Anesthesiology and Intensive Care Medicine, Campus Virchow-Klinikum and Campus Charité Mitte, Charité - Universitaetsmedizin Berlin

🇩🇪

Berlin, Germany

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