Diurnal and segmental variation in glucose sensing: effects on homeostasis, satiety and energy intake in healthy volunteers - Diurnal and segmental variation in glucose sensing

niversiteit Maastricht0 个研究点目标入组 36 人开始时间: 待定最近更新: 2024年5月13日

适应症

试验速览

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•Healthy male or female, aged 18-55 years and a Body Mass Index (BMI) of 18-29 kg/m2

•Evidence of severe diseases, allergy, major surgery and/or laboratory assessments which might limit participation in or completion of the study protocol. Gastrointestinal or hepatic disorders influencing gastrointestinal absorption or transit. Use of psychotropic drugs. Alcohol in excess of 21 units/week for males and 14 units/week for females. Concomitant medication that can increase gastric pH, or alter gastric emptying, or alter intestinal transit, or influence satiety/energy intake. Pregnancy, lactation, wish to become pregnant during study, or having a positive pregnancy test at inclusion. Reported unexplained weight loss/gain of more than 2 kg in the month before the study enrollment. Score > 9 on Factor 1 (dietary restrained) of the Dutch translation of the Three Factor eating Questionnaire (TFEQ). Blood donations less than three months previous to study enrollment. One or more of the following dietary habits: medically prescribed diets, weight reduction diets, or vegetarian/macrobiotic/biologically dynamic food habits. Reported working on late/night shifts.

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