跳至主要内容
临床试验/CTRI/2024/05/067257
CTRI/2024/05/067257尚未招募2/3 期

“A Randomized Comparative Clinical Study to Evaluate the Efficacy of Yapana Basti and Shashti Shali Pinda Swedana with and without Nasya Karma followed by Shaman in the Management of Sarvanga Vatavyadhi with special reference to Amyotrophic Lateral Sclerosis.”

National Institute of Ayurveda1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2024年6月30日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
入组人数
30
试验地点
1
主要终点
Changes will be assessed on the basis of the ALS Functional

研究概览

简要总结

Introduction:

Since the beginning of time, sickness and man have been rivals. Man has waged an unrelenting war against his enemies in an effort to protect his health, treat sickness, alleviate suffering and extend life despite disabilities. Ayurvedic treatmens, particularly panchkarma have become increasingly popular as a result of the strong basis of the holistic approach upon which the entire edifice of Ayurveda is based. In order to provide some sort of symptomatic and supportive treatment fo maintaining the quality of life, motor neuron diseases are a group of prrogressive neurological disorders that call for a variety of applicaations, modalities and interventions, including occupational therapy, physical and speech therapies.

Shodhana and Shamana are the two primary therapeutic methods used in Ayurveda. Shodhana therapy is regarded as the best since it aids in the entire eradication of vitiatied Doshaa, preventing the ailment from reoccurring like uprooting weeds by the roots. In order to restore internal equilibrium. The Motor neurons of the CNS, particularly those in the pyramidal and extrapyramidal tracts, degenerate in MND. MND patients may benefit from Panchkarma treatment. One Panchkarma treatment, Sarvanga Shashti Shali Pinda Swedana targets particulaarly Vata predominant illnesses. Sarvanga Shashti Shali Pinda Swedana performed over the whole body is helpful for MND related muscle weakness. Basti is regarded as the most effective shodhana procedure due to its broad applicability and mulitfaceted therapeutic effects. Acharyas refer to it as Ardha Chikitsa in Ayurveda and it is relevant to all. A type of Basti called Yapana Basti possess Snehana and Shodhana qualities. It is indicated in both healthy and unhealthy situations. Yapana Basti is thought to have Rasayana propertiees and to build up the muscles.

Need for Study: MND is one of the most severe disorders of the nervous system that causes severe problems for those who have it, on a social, personal and financial level. Other than supporting measures, no medical system has yet developed an effective management strategy. Thus this study aims to evaluate the treatment of Ayurveda in the disease.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
20.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • (a) Diagnosed cases of Amyotrophic Lateral Sclerosis, having less than five years onset.
  • (b) Patients will be selected from the age group of 20-60 years, irrespective of sex, religion and occupation etc.
  • (c) Patients of ALS who are willing to participate in an interventional study.
  • (d) Patients willing to sign the informed consent form.

排除标准

  • (a) Patients with brain lesions.
  • (b) Patients with systemic or endocrine disorders.
  • (c) Patients with severe respiratory distress.
  • (e) Patients having other neurological degenerated diseases.
  • (f) Patients not willing to sign the informed consent form.

结局指标

主要结局

Changes will be assessed on the basis of the ALS Functional

时间窗: Day 0 (Baseline), Day 30, and Day 75 (Follow-up)

Rating Scale- Revised (ALSFRS-R) and Norris scale.

时间窗: Day 0 (Baseline), Day 30, and Day 75 (Follow-up)

次要结局

  • Relief in other symptoms of Amyotrophic Lateral Sclerosis.(75days)

研究者

申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Avvinish Narine

National Institute of Ayurveda, (DU), Jaipur.

研究点 (1)

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