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临床试验/NCT01478919
NCT01478919已完成不适用

Risk Factors for Local Residual Neoplasia After Convetional Endoscopic Mucosal Resection of Laterally Spreading Tumors

Vitkovice Hospital1 个研究点 分布在 1 个国家目标入组 127 人开始时间: 2010年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
127
试验地点
1
主要终点
Occurence of Local Residual Neoplasia (LRN)

研究概览

简要总结

Laterally Spreading Tumors (LST) are important precursosrs of invasive colorectal cancer. Endoscopic treatment has replaced surgery in most of the cases. Nevertheless, after conventional Endoscopic Mucosal Resection (CER), Local Residual Neoplasia (LRN) is an issue. Therefore, endoscopic follow-up and treatment are necessary. To decrease its occurrence, the risk factors of LRN shoudl be identified. Thereafter, in high-risk patients, other modalities of initial treatment including Endoscopic Submucosal Dissection (ESD) and surgical treatment, could be considered. The purpose of this prospective study is to identify risk factors associated with the presence of LRN after CER of LSTs.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • all consecutive patients referred for EMR of LST

排除标准

  • polyposis syndromes
  • previous therapeutic attempt

结局指标

主要结局

Occurence of Local Residual Neoplasia (LRN)

时间窗: 3 months

LRN was defined as a histologically confirmed neoplastic tissue in the biopsy samples obtained from post-resection scar during follow-up colonoscopy 3 months after endoscopic resection

次要结局

  • Evaluation of Selected Risk Factors for Local Residual Neoplasia (LRN)(3 months)

研究者

发起方
Vitkovice Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Premysl Falt MD

Investigator

Vitkovice Hospital

研究点 (1)

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