Risk Factors for Residual Neoplasia After Endoscopic Mucosal Resection
- Conditions
- Colorectal Cancer
- Registration Number
- NCT01478919
- Lead Sponsor
- Vitkovice Hospital
- Brief Summary
Laterally Spreading Tumors (LST) are important precursosrs of invasive colorectal cancer. Endoscopic treatment has replaced surgery in most of the cases. Nevertheless, after conventional Endoscopic Mucosal Resection (CER), Local Residual Neoplasia (LRN) is an issue. Therefore, endoscopic follow-up and treatment are necessary. To decrease its occurrence, the risk factors of LRN shoudl be identified. Thereafter, in high-risk patients, other modalities of initial treatment including Endoscopic Submucosal Dissection (ESD) and surgical treatment, could be considered. The purpose of this prospective study is to identify risk factors associated with the presence of LRN after CER of LSTs.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 127
- all consecutive patients referred for EMR of LST
- polyposis syndromes
- previous therapeutic attempt
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Occurence of Local Residual Neoplasia (LRN) 3 months LRN was defined as a histologically confirmed neoplastic tissue in the biopsy samples obtained from post-resection scar during follow-up colonoscopy 3 months after endoscopic resection
- Secondary Outcome Measures
Name Time Method Evaluation of Selected Risk Factors for Local Residual Neoplasia (LRN) 3 months Evaluation of selected patient- and lesion-related risk factors associated with LRN (gender, age, lesion size, location, morphology, pit pattern, histology, type of resection, and others)
Trial Locations
- Locations (1)
Vitkovice Hospital
🇨🇿Ostrava, Czech Republic