Prehabilitation Physical Activity in Persons With Osteoarthritis

Phase 4

Completed

• Conditions: Osteoarthritis
• Interventions: Other: therapeutical exercises

• Registration Number: NCT02881463
• Lead Sponsor: University of Tartu

Brief Summary

Knee joint osteoarthritis (OA) reduces functional mobility and performance of daily tasks such as rising from a chair. Therefore interventions aimed at improving muscle strength and sit-to-stand task performance are very important for these patients. The effect of exercise programs, including home exercise programs (HEP), on muscle strength, joint pain and function is well known and widely researched, yet not many studies have investigated the effect of an HEP on electromyographic activity (EMG) of muscles when performing everyday tasks, such as rising from and sitting on a chair. The aim of this study was to investigate effect of prehabilitation in women with severe knee joint OA scheduled for knee joint arthroplasty (TKA).

Detailed Description

Not available

Study Timeline

• Study Start: 2013-01
• Primary Completion: 2016-06
• Study Completion: 2016-06
• Study First Submitted: 2016-06-16
• Study First Submitted QC: 2016-08-23
• Study First Posted: 2016-08-29
• Status Verified: 2016-09
• Last Update Submitted: 2016-09-12
• Last Update Posted: 2016-09-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 45

Inclusion Criteria

• For OA patients: patients with severe knee joint OA undergoing unilateral total knee arthroplasty (TKA)
• for controls: pain of joints more than 20/100 mm by VAS

Exclusion Criteria

For both groups:

• previous total joint arthroplasty of lower limbs
• other musculoskeletal, neurological and cardiovascular diseases
• any diseases affecting balance and coordination.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Home Exercise Program	therapeutical exercises	8- week therapeutical exercise program performing at home for women with knee joint osteoarthritis

Primary Outcome Measures

Name	Time	Method
Muscle electromyographic (EMG) activity	up to 12 months	Electromyographic (EMG) activity of thigh muscles during gait and sit to stand task (amplitude, mV)

Secondary Outcome Measures

Name	Time	Method
Knee joint pain intensity	up to 12 months	Self-reported knee joint pain intensity measured by visual-analogue scale (VAS) (in mm: "0 mm" - no pain and "100 mm" - extreme pain)
Knee joint function	up to 12 months	Self-reported functional status measured by Knee Injury and Osteoarthritis Outcome Score (KOOS) - Symptoms, Pain, Daily Living Activity, Sport and Recreational Activity. Quality of Life. Maximum is 100 points (complains are absent) and minimum is 0 points (extreme complains)
Sit to Stand test	up to 12 months	five time Sit to Stand test from standard chair (s)
Mobility test	up to 12 months	Timed Up and Go test, 3-m plus return 3-m walking test (s)
Leg muscles strength	up to 12 months	strength of leg extensor muscles (N)
Body balance	up to 12 months	Body postural sway measuring during standing using Kistler force plate (Switzerland) (mm), eyes open and eyes closed
Gait pattern	up to 12 months	Gait kinematic characteristics measurement using three-dimensional movement analysis system and six optoelectronic cameras (BTS S.p.A. Italy) - joint angles (degrees)