跳至主要内容
临床试验/CTRI/2025/09/094237
CTRI/2025/09/094237尚未招募不适用

AS- OCT as a tool for assessing filtering bleb function

Dr Shraddha Lazar Arattukulam1 个研究点 分布在 1 个国家目标入组 79 人开始时间: 2025年9月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
79
试验地点
1
主要终点
To assess the parameters of well functioning bleb on AS-OCT.

研究概览

简要总结

Glaucoma describes a group of conditions in which there is characteristics cupping of the optic disc corresponding viual feild defects due to retinal ganglion cell loss with iop being the only modifiable risk factor.

iop control after trabeculectomy depends on aqueous outflow and absorption from the bleb . The outcome depends upon a functioning filterring bleb . Hence bleb mmorphology is an important parameter to assess bleb function and predeict ble related complication .

However the major limitation of slit lamp assessment is the inability to image intrableb morphology and subjectivity of clinical grading .

In our study we will be using ANTERION AS-OCT which shows the internal belb structure such as bleb wall refelctivity , thickness , bleb wall height , internal cavity height , internal cavity extent and trabeculectomy opening size to assess bleb morphology and to predict bleb function and assess bleb related complications.

79 patient attending the opd who are diagnosed cases of glaucoma undergoing trab or trab with iol will be assesed after fulffiling the inclusion and exclusion criteria ,written informed consent will be taken.

Patent will undergo regular glaucoma evaluvation includng gat and gonioscopy preop and will undergo bleb analysis with as -oct two scans will be taken, a radial section perpendicular to limbus through the site pf pi and a  tangential section  to the limbus through the site of maximal bleb elevation to assess the morphological characteristics of the bleb and if there is any need for early intervention

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Male and femal patients who are above 18 years of age, diagnosed as glaucoma and undergoing trabeculectomy or combined trabeculectomy and cataract surgery.

排除标准

  • Patient with orbit , corneal or ocular diseases that could affect the IOP.
  • Patients not regular with follow ups and likely to be lost to follow ups.

结局指标

主要结局

To assess the parameters of well functioning bleb on AS-OCT.

时间窗: 2 WEEKS , 1 MONTH AND 3 MONTHS

次要结局

未报告次要终点

研究者

发起方
Dr Shraddha Lazar Arattukulam
申办方类型
Other [SELF ]
责任方
Principal Investigator
主要研究者

Dr.Shraddha Lazar Arattukulam

Sankara Eye Hospital

研究点 (1)

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