The Pharmacogenetics of Oxycodone analgesia in human experimental pain models
Phase 1
- Conditions
- Healthy volunteers
- Registration Number
- EUCTR2005-004082-42-DK
- Lead Sponsor
- Søren Sindrup, Dept. of Neurology, University Hospital of Odense
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 32
Inclusion Criteria
Healthy volunteer between 20 and 40 years.
Healthy according to medical history and physical examination.
Informed consent given.
Phenotyped or genotyped as extensive or poor metabolizer of sparteine.
Female: Does the volunteer use safe contraception (IUD, gestagen injectiones or
oral contraception) or test negative in u-HCG.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
Any known allergy or intolerance to oxycodone.
Regularly drug therapy or medication (except contraceptives).
Alcohol or medicine abuse.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method