Analysis of neuropathology of localization-related epilepsy by PET using an inflammatory ligand, [11C]-DPA713

Not Applicable

Recruiting

• Conditions: localization related epilepsy

• Registration Number: JPRN-UMIN000024167
• Lead Sponsor: Ministry of Education, Culture, Sports, Science and Technology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-10-15
• Last Update Posted: 17 October 2023
• Study Completion: 2025-03-31

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Not provided

Exclusion Criteria

1)Patients with severe hepatic and/or renal dysfunction 2) Woman who is pregnant, breast-feeding and may become pregnant. 3) The patients whose attending physician jugged that participating in this study as inadequacy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
We will qualitatively estimate the uptake of [11C]-DPA713 in a human brain.

Secondary Outcome Measures

Name	Time	Method
1)We will analyze the association of [11C]DPA713 data and other clinical data, such as clinical manifestation, EEG, MRI, FDG-PET, Iomazenil-SPECT, and MEG. 2)In the patients who undergo epilepsy surgery, the severity of microglial activation is studied by a neuropathological way.