Differences Between Suicide Attempters and Suicide Ideators. Influence of the Brief Therapy ASSIP on Neuropsychological Correlates and Psychological Process Factors (NePsyASSIP HT) - Project 1
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 180
- 试验地点
- 1
- 主要终点
- Differences in Inhibitory Control
研究概览
简要总结
The present study consists of 3 projects in total and aims to investigate the (neuro-) psychological patterns from suicidal ideation to suicidal behavior as well as the effects and feasibility of ASSIP Home Treatment.
The overall aim of project 1 is to determine (neuro-) psychological differences between suicide attempters, suicide ideators, a clinical control group, and healthy controls. Study participants in project 1 will participate in a one-time (neuro-) psychological assessment.
Project 1 of this study is an observational cross-sectional study with four groups that will be conducted at the University Hospital of Psychiatry and Psychotherapy Bern (Switzerland): Patients with at least one suicide attempt in their past (SUAT), patients with suicidal ideation (SUID), patients from the same clinical cohort, without neither suicidal behavior or ideation (CLIN) and the healthy group (HLTH). The cohorts to be examined (SUAT & SUID) will be compared to the two control groups (CLIN & HLTH). Only people who have signed the informed consent and meet the eligibility criteria can participate in this study.
详细描述
Purpose and aims:
The present study consists of 3 projects in total and aims to investigate the (neuro-) psychological patterns from suicidal ideation to suicidal behavior as well as the effects and feasibility of ASSIP Home Treatment.
The aim of this project is to distinguish the (neuro-) psychological patterns of suicide ideators from suicide attempters by investigating four experimental groups. For this purpose, neuropsychological functioning, as well as psychological process factors, are analyzed. Patients with at least one prior suicide attempt are compared to patients with suicidal ideation, to a clinical control group, as well as to healthy controls. For this project, patients who are being treated at the University Hospital of Psychiatry and Psychotherapy Bern (Switzerland) at the time of the project will be requested. Afterwards, participants with a suicide attempt in their history will also be asked to participate in the longitudinal part of the study, which is Project 2.
Background:
In Switzerland, approximately three people die by suicide every day, and suicide attempts exceed this number by far. As a previous suicide attempt is one of the strongest predictors of a completed suicide, it is of utmost importance to identify the people at risk. However, research has shown that traditional risk factors (e.g., depression, psychiatric disorder, etc.) reliably predict suicidal ideation but poorly predict suicidal behavior. Furthermore, while effective suicide-specific interventions exist, up to 50% of the suicide attempters reject the recommended treatment, and around 60% discontinue treatment after one session. Hence, a different approach is required. In this study, three projects will be conducted. In Project 1, (neuro-) psychological patterns of suicide attempters will be identified by comparing the following four different groups:
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Subjects fulfilling the following inclusion criteria are eligible for the study:
- •Informed consent as documented by signature
- •Age ≥ 18 years
- •Additional inclusion criterion for the SUAT group in project 1:
- •At least one previous suicide attempt
- •Additional inclusion criterion for the SUID group in project 1:
- •Suicidal ideation
- •Additional inclusion criterion for the CLIN group in project 1:
- •Current psychiatric disorder treated on an inpatient, day-care or outpatient basis For the HLTH group, no further inclusion criteria are formulated.
排除标准
- •The presence of any one of the following exclusion criteria leads to exclusion of the subject:
- •Serious cognitive impairment
- •Any current psychotic disorder
- •Any current medication, which substantially impairs the attention span, reaction rate or any other relevant cognitive functions
- •Inability to follow the procedures of the study (e.g., insufficient mastery of the German language, previous enrolment into the current study)
- •Additional exclusion criterion for the SUID group:
- •Previous suicidal behavior
- •Additional exclusion criteria for the CLIN and HLTH groups:
- •Previous suicidal behavior
- •Suicidal ideation
- •Additional exclusion criterion for the HLTH group:
- •Current psychiatric disorder treated on an inpatient, day-care or outpatient basis
研究组 & 干预措施
Suicide attempters
Patients with at least one previous suicide attempt
干预措施: (Neuro-)psychological assessment (Other)
Suicide ideators
Patients with suicidal thoughts, but no previous suicide attempt
干预措施: (Neuro-)psychological assessment (Other)
Clinical control group
Patients without suicidal behavior and thoughts
干预措施: (Neuro-)psychological assessment (Other)
Healthy controls
Healthy persons without suicidal behavior and thoughts
干预措施: (Neuro-)psychological assessment (Other)
结局指标
主要结局
Differences in Inhibitory Control
时间窗: The assessment takes place 1 day to 1 week after informed consent.
The Go/No-Go task is a cognitive task to assess an individual's ability to inhibit a prepotent response. It is used to measure impulse control and response inhibition. The task requires participants to respond ("Go" response) to one type of stimulus and to withhold or inhibit their response ("No-Go" response) to another type of stimulus. The Go/No-Go task yields measures such as reaction time, accuracy, and the ability to inhibit responses. Reaction times can vary widely, and accuracy is often expressed as a percentage of correct responses. Lower reaction times and higher accuracy in withholding responses (No-Go trials) indicate better inhibitory control and cognitive performance.
次要结局
- Selective Attention and Interference Control(The assessment takes place 1 day to 1 week after informed consent.)