the placental transfusion in cut-umbilical cord milking vs Early cord clamping
Phase 3
- Conditions
- Health Condition 1: I999- Unspecified disorder of circulatory system
- Registration Number
- CTRI/2024/01/061865
- Lead Sponsor
- DEPARTMENT OF NEONATOLOGY
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
during the delivery time
Exclusion Criteria
i.Neonates born at gestation less than 30weeks or more than or equal to 37 weeks
ii.Outborn neonates
iii.Major lethal congenital anomalies or known/suspected chromosomal anomalies
iv.Fetal hydrops
v.Rh isoimmunization
vi.Cord prolapse, cord abnormalities such as true knots
vii.Twin-to-twin transfusion syndrome
viii.Discordant twins (a weight difference of >20%)
ix.Short umbilical cord length
x.Noparentalconsent
xi.Residence beyond 20 kms radius from our unit.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine venous hematocrit at 48 (+/- 4 ) hours of <br/ ><br>postnatal age <br/ ><br>Timepoint: To determine venous hematocrit at 48 (+/- 4 ) hours of <br/ ><br>postnatal age <br/ ><br>
- Secondary Outcome Measures
Name Time Method a.Hct and serum ferritin at 6weeks of postnatal age <br/ ><br>b.Hb,hct and bilirubin level at 12,48hours of postnatal age. <br/ ><br>c.Heartrate, mean bloodpressure in the first 48 hours of life <br/ ><br>d.Hyperbilirubinemia requiring phototherapy <br/ ><br>e.Symptomatic polycythemia in first 48 hours <br/ ><br>f.Incidence of hemodynamically significant patent ductus arteriosus,NEC (Stage 2 and above), IVH on cranial ultrasound(grade3andabove), ROP(stage2andabove) and BPD <br/ ><br>g.Total number of PRBC transfusions till 6 weeks of postnatal age <br/ ><br>h.Duration of hospital stay <br/ ><br>i.Death up to 6weeks of postnatal age <br/ ><br>Timepoint: 6 weeks post-natal age