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临床试验/ACTRN12617001119381
ACTRN12617001119381招募中未知

Circulating Tumour DNA as a Marker of Residual Disease and Response to Adjuvant Chemotherapy in Stage I - IV Epithelial Ovarian, Fallopian Tube and Primary Peritoneal Cancer (EOC)

Walter and Eliza Hall Institute of Medical Research0 个研究点目标入组 100 人开始时间: 2017年7月31日最近更新:
适应症

试验速览

阶段
未知
状态
招募中
发起方
入组人数
100

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 Years 至 o limit(—)
性别
Female

入选标准

  • 1. Patients that have had primary debulking surgery for curatively resected stage I-IV high grade serous, endometrioid or clear cell carcinoma, or carcinosarcoma of the ovary, fallopian tube or primary peritoneum. Stage IV patients can only be included in the study if they have had a complete resection of all macroscopic disease with no residual disease.
  • Patients commencing neoadjuvant chemotherapy for stage I-
  • III high grade serous, endometrioid or clear cell carcinoma, or carcinosarcoma of the ovary, fallopian tube or primary peritoneum. Women must be planned to undergo interim debulking surgery.
  • 2. A representative tumour sample can be made available for molecular testing after surgery or a core biopsy pre neoadjuvant chemotherapy if available.
  • 3. Fit and planned for adjuvant chemotherapy.

排除标准

  • 1. History of another primary cancer within the last 3 years,
  • with the exception of non-melanomatous skin cancer,
  • carcinoma in situ of the cervix and fully resected stage1a
  • endometrial cancer
  • 2. Patients with EOC of mucinous subtype and sarcoma
  • 3. Patients with Stage IV disease who have residual disease
  • 4. Patients <18 years

研究者

发起方
Walter and Eliza Hall Institute of Medical Research

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