NL-OMON33407已完成不适用
The role of intestinal integrity and inflammation in the pathogenesis of insulin resistance and non-alcoholic steatohepatitis in morbid obesity. - Intestinal permeability in diabetes type 2 and fatty liver disease
Medisch Universitair Ziekenhuis Maastricht0 个研究点目标入组 190 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 190
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Researchpopulation:
- •BMI >40 or BMI>35 kg/m2 with co-morbidities
- •planned for bariatric surgery
- •Age 18-60 years (to prevent inclusion of patients who are unable to give informed consent and to have inclusion criteria adjusted to the criteria for surgical intervention)
- •Control population:
- •BMI 20-25
- •planned for Nissen fundoplication or cholecystectomy
- •Age 18-60 years old
排除标准
- •For all patients:
- •Age <18 or >60 years
- •Diabetes Mellitus type I
- •Inflammatory diseases such as auto-immune diseases (due to a higher inflammatory profile)
- •Degenerative disase
- •Alcohol or drug abuse
- •use of corticosteroids and / or prednisolone (confounding effect on inflammatory status)
研究者
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