Effect of Different Remineralization Gels

Not Applicable

Not yet recruiting

• Conditions: White Spot Lesion

• Registration Number: NCT05868603
• Lead Sponsor: Marmara University

Brief Summary

The aim of the study is to treat white spot lesions that occur after orthodontic treatment.

Different gels will be used for remineralization. The study will consist of 45 people between the ages of 15-18. 45 people will be divided into 3 groups.

Detailed Description

Oral hygiene training will be given to each group and a toothpaste containing 1450 ppm fluoride will be given to brush their teeth twice a day.

Essix appliance with reservoir will be made by taking impressions from 30 patients. Remineralization gel will be put into the Essix appliance for 5-7 minutes twice a day for one month.

Study Timeline

• Study First Submitted: 2023-04-24
• Status Verified: 2023-05
• Study First Submitted QC: 2023-05-11
• Last Update Submitted: 2023-05-11
• Study First Posted: 2023-05-22
• Last Update Posted: 2023-05-22
• Study Start: 2023-05-24
• Primary Completion: 2024-10-01
• Study Completion: 2025-04-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

• Patients aged 15-18 years,
• Presence of white point lesions,
• Volunteering to participate in the research.

Exclusion Criteria

• Not having received orthodontic treatment,
• Having a developmental anomaly affecting the enamel,
• Being allergic to milk,
• Having a syndrome affecting the oral cavity.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP)	4 weeks	Decrease in laser fluorescence values with Diagnodent Pen as an indicator of remineralization

Secondary Outcome Measures

Name	Time	Method
Calcium glycerophosphate	4 weeks	Decrease in laser fluorescence values with Diagnodent Pen as an indicator of remineralization