Effect of Different Remineralization Gels
- Conditions
- White Spot Lesion
- Interventions
- Other: Remineralization gel
- Registration Number
- NCT05868603
- Lead Sponsor
- Marmara University
- Brief Summary
The aim of the study is to treat white spot lesions that occur after orthodontic treatment.
Different gels will be used for remineralization. The study will consist of 45 people between the ages of 15-18. 45 people will be divided into 3 groups.
- Detailed Description
Oral hygiene training will be given to each group and a toothpaste containing 1450 ppm fluoride will be given to brush their teeth twice a day.
Essix appliance with reservoir will be made by taking impressions from 30 patients. Remineralization gel will be put into the Essix appliance for 5-7 minutes twice a day for one month.
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 45
- Patients aged 15-18 years,
- Presence of white point lesions,
- Volunteering to participate in the research.
- Not having received orthodontic treatment,
- Having a developmental anomaly affecting the enamel,
- Being allergic to milk,
- Having a syndrome affecting the oral cavity.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Remineralization gel with calcium glycerophosphate (R.O.C.S.® Medical Mineral Gel, Russia) Remineralization gel Remineralization gel containing calcium glycerophosphate (R.O.C.S.® Medical Minerals Gel, Russia) will be put into the Essix appliance with a reservoir for 5-7 minutes twice a day for one month. Before and after the applying remineralization gel, the laser fluorescence values will measure with a DIAGNOdent pen( KaVo Dental corporation, East Main street Lake Zurich, lL). Remineralization gel with CPP- ACP (GC Tooth MousseTM, Tokyo, Japan) Remineralization gel CPP-ACP containing remineralization gel (Tooth Mousse GC, Tokyo, Japan) will be put into the Essix appliance with a reservoir and applied for 5-7 minutes twice a day for one month. Before and after the applying remineralization gel, the laser fluorescence values will measure with a DIAGNOdent pen (KaVo Dental corporation, East Main street Lake Zurich, lL).
- Primary Outcome Measures
Name Time Method Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) 4 weeks Decrease in laser fluorescence values with Diagnodent Pen as an indicator of remineralization
- Secondary Outcome Measures
Name Time Method Calcium glycerophosphate 4 weeks Decrease in laser fluorescence values with Diagnodent Pen as an indicator of remineralization