Assessment of the effect of boron citrate supplementation in the prevention and treatment of obesity

Not Applicable

• Conditions: Obesity.; Obesity due to excess calories; E66.0

• Registration Number: IRCT20090609002017N36
• Lead Sponsor: Tabriz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 3 April 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Ages between 18 to 60 years
body mass index (BMI) 30 to 40 kg/m2
Residence in Tabriz

Exclusion Criteria

Smokers
Consuming alcohol
Individuals taking chemical or herbal drugs for weight loss, hepatotoxic drugs, anti-hypertensive drugs, lipid-lowering and anti-diabetic drugs, corticosteroid, and non-steroidal anti-inflammatory drugs and antibiotics.
Individuals who are pregnant, lactating, menopause, and those who use birth control pills and estrogen
Individuals who have some pathologic conditions such as cardiovascular, liver, thyroid, parathyroid, kidney, gastrointestinal tract and autoimmune diseases as well as suffering from polycystic ovary syndrome, cancer and inflammatory disease
Individuals who underwent weight loss surgery in the last year or weight loss diets in the last three months

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
PPAR-? gene expression. Timepoint: The beginning and end of the study. Method of measurement: Measurement of gene expression by RT-PCR method.;SIRT1 gene expression. Timepoint: The beginning and end of the study. Method of measurement: Measurement of gene expression by RT-PCR method.;PGC-1a gene expression. Timepoint: The beginning and end of the study. Method of measurement: Measurement of gene expression by RT-PCR method.;AMPK gene expression. Timepoint: The beginning and end of the study. Method of measurement: Measurement of gene expression by RT-PCR method.