The effects of intermittent fasting diet alone or in combination with probiotic supplementation in comparison with calorie-restricted diet in patients with polycystic ovary syndrome

Not Applicable

Recruiting

• Conditions: Polycystic ovary syndrome.; Polycystic ovarian syndrome; E28.2

• Registration Number: IRCT20121110011421N5
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 November 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 90

Inclusion Criteria

Diagnosis of PCOS based on Rotterdam criteria for the first time
Body mass index between 25 and 35 kg/m2
People who definitely eat breakfast (early breakfast)
Have a smartphone
Age range between 18 and 40 years

Exclusion Criteria

Smoking
Alcohol drinking
Taking OCP drugs, anti-androgens, metformin, lipid and blood pressure lowering drugs
Pregnancy and breastfeeding
Women who intend to become pregnant or take drugs such as chloramifel, letrozole and gonadotropin
Menopausal women
Antibiotic use in the last three months
Consumption of probiotic products
Night shift workers
Intestinal malabsorption (history of bariatric surgery, inflammatory bowel disease, celiac disease)
Inability to fast due to overnight medication
Suffering from other diseases such as kidney disease, liver disease, cancer, heart disease and acute and chronic infectious diseases, type 1 and 2 diabetes, Cushing's disease, acromegaly, gigantism

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Weight. Timepoint: Before intervention and 8 weeks after intervention. Method of measurement: Digital scale.;HOMA- IR. Timepoint: Before intervention and 8 weeks after intervention. Method of measurement: HOMA- IR= insulin × glucose/405.