The effects of single leg immobilization on muscle protein synthesis, protein breakdown, and glucose uptake in healthy young me
- Conditions
- Immobilization, muscle wasting
- Registration Number
- NL-OMON26917
- Lead Sponsor
- McMaster University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 8
Inclusion Criteria
1) Healthy males, between the ages of 18 and 30 y
2) BMI between 18.5 and 30.0 kg/m2
Exclusion Criteria
1) The use of anti-inflammatory and/or analgesic medication, whether it is prescription or not
2) A history of neuromuscular disorders or muscle/bone wasting diseases
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1)The effect of single leg immobilization on basal and postprandial skeletal muscle protein synthesis <br /><br>2)The effect of single leg immobilization on basal and postprandial skeletal muscle protein breakdown<br /><br>3)The effect of single leg immobilization on rates of skeletal muscle glucose uptake <br>
- Secondary Outcome Measures
Name Time Method 1)The effect of single leg immobilization on muscle mass, muscle strength, and body composition<br /><br>2)The effect of single leg immobilization on integrated (chronic) rates of muscle protein synthesis<br>