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临床试验/CTRI/2025/04/085848
CTRI/2025/04/085848尚未招募4 期

Comparing the effect of Argyreia speciosa gel, Curcumin gel, Triphala gel and non- eugenol periodontal dressing on wound healing and pain post periodontal flap surgery-A randomized clinical trial

未提供1 个研究点 分布在 1 个国家目标入组 15 人开始时间: 2025年5月15日最近更新:

试验速览

阶段
4 期
状态
尚未招募
入组人数
15
试验地点
1
主要终点
Early wound healing, post operative pain perception will be assessed.

研究概览

简要总结

Aim of this study is to compare effect of Argyreia Speciosa gel, Curcumin gel, Triphala gel and Non –eugenol periodontal dressing on wound healing and pain following periodontal flap surgery-A randomized clinical trial. After obtaining thorough case history and written informed consent from the patients enrolled in the study (considering all inclusion and exclusion criteria) each patient would undergo the required periodontal flap surgery. After the surgical procedure, randomization and quadrant allotment for either Topical application of Argyreia speciosa gel or Triphala gel or Curcumin gel or non-eugenol periodontal dressing will be done. For periodontal dressing group, COE-PAK will be mixed and applied, according to manufacturer instructions. For Argyreia speciosa gel group, Triphala gel group and Curcumin gel group, the gels will be applied to respective quadrants immediately by the clinician and also will be given to the patient to apply as directed on the operated site twice daily for the next 7 days. Patients failing to comply with timely application of Argyreia speciosa gel, Triphala gel, Curcumin gel as instructed will be excluded from the study. After 1 week the pack and sutures will be removed by the same operator. Early Healing Score (EHS)after 1st and 2nd week and VAS after 1st and 2nd week will be recorded by second blinded operator. The time period between periodontal flap surgeries will be at least 3 weeks.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Investigator Blinded

入排标准

年龄范围
20.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • 1.Patients with moderate to severe chronic periodontitis 2.Pocket probing depth greater than or equal to 5mm.
  • 3.Systemically healthy patients fit for periodontal surgery 4.Patients with good oral hygiene maintenance.

排除标准

  • 1.Patients with present or past systemic illnesses known to affect the outcomes of periodontal therapy.
  • 2.Immunocompromised patients.
  • 3.Patients taking medications that may interfere with periodontal therapy.
  • 4.Pregnant patients.
  • 5.Patient with any allergic tendencies pertaining to treatment.
  • 6.Deleterious oral habits.
  • (E.g. Smoking, alcohol consumption etc.).

结局指标

主要结局

Early wound healing, post operative pain perception will be assessed.

时间窗: first and second week

次要结局

未报告次要终点

研究者

发起方
未提供
责任方
Principal Investigator
主要研究者

Dr Soniya Arvind Waghmare

SMBT Dental College and Hospital Sangamner

研究点 (1)

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