MedPath

Actual Use Study of Tamsulosin in Men

Phase 3
Completed
Conditions
Urological Manifestations
Interventions
Registration Number
NCT02573311
Lead Sponsor
Boehringer Ingelheim
Brief Summary

An actual use study to assess how men who respond to advertisements about urinary symptoms use tamsulosin in a simulated Over the Counter (OTC) setting including following "stop use and ask a doctor if" and "ask a doctor before use" statements and if they take the medication according to the label instructions, also assess any reported adverse events during simulated OTC use.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Male
Target Recruitment
1117
Inclusion Criteria

Not provided

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Exclusion Criteria

Not provided

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Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
mentamsulosin hydrochloride-
Primary Outcome Measures
NameTimeMethod
Percentage of Men Who Report a Condition Listed Under the "Stop Use and Ask a Doctor if" Section of the DFL Within the First 12 Weeks of Using Study Product and do Not Stop Use or Initiate Contact With Doctor Out of Total Population in Cohort 112 weeks

Percentage of men who reported a condition listed under the "Stop use and ask a doctor if" section of the Drug Facts Label (DFL) within the first 12 weeks of using study product and did not stop use or initiated contact with a doctor out of the total population is presented along with 95% exact two sided Clopper-Pearson confidence interval.

Secondary Outcome Measures
NameTimeMethod
Percentage of Men Who Report Condition Listed Under "Stop Use and Ask a Doctor if" Section of the DFL and do Not Stop Use or Initiate Contact With Doctor Out of the Total Population in Cohort 1 Who Report the Condition Within 12 WeeksWeek 12

Percentage of men who reported a condition listed under the "Stop use and ask a doctor if" section of the DFL within 12 weeks of using study product and did not stop use or initiated contact with a doctor out of the total population of men in Cohort 1 who reported a condition listed under the "Stop use and ask a doctor if" section of the DFL within 12 weeks of using study product is presented along with 95% exact two sided Clopper-Pearson confidence interval.

Percentage of Men Who Report Condition Listed Under "Stop Use and Ask a Doctor if" Section of the DFL and do Not Stop Use or Initiate Contact With Doctor Out of the Total Population in Cohort 1 Who Report the Condition Within 24 WeeksWeek 24

Percentage of men who reported a condition listed under the "Stop use and ask a doctor if" section of the DFL within 24 weeks of using study product and did not stop use or initiated contact with a doctor out of the total population of men in Cohort 1 who reported a condition listed under the "Stop use and ask a doctor if" section of the DFL within 24 weeks of using study product is presented along with 95% exact two sided Clopper-Pearson confidence interval.

Percentage of Men Who Took Two or More Capsules Per Day Within the First 12/24 Weeks of Using Study Product Out of the Total Population in Cohort 1Week 12 and Week 24

Percentage of men who took two or more capsules per day within the first 12/24 weeks of using study product out of the total population of men in Cohort 1 is presented along with 95% exact two sided Clopper-Pearson confidence interval

Percentage of Men Who Report a Condition Listed Under the "Stop Use and Ask a Doctor if" Section of the DFL During the Study (24 Weeks) and do Not Stop Use or Initiate Contact With a Doctor Out of the Total Population in Cohort 124 weeks

Percentage of men who reported a condition listed under the "Stop use and ask a doctor if" section of the DFL during the study (i.e., 24 weeks) and did not stop use or initiated contact with a doctor out of the total population of men in Cohort 1 is presented along with 95% exact two sided Clopper-Pearson confidence interval.

Percentage of Men Who Seek the Advice of a Physician Within the First 12/24 Weeks of the Study Out of the Total Population in Cohort 1Week 12 and Week 24

Percentage of men who sought advice of a physician within the first 12/24 weeks of the study out of the total population of men in Cohort 1 is presented along with 95% exact two sided Clopper-Pearson confidence interval

Percentage of Men Who Report a Condition Listed Under the "Stop Use and Ask a Doctor if" Section of the DFL Within the First 12 Weeks of Using Study Product Out of the Total Population in Cohort 112 weeks

Percentage of men who reported a condition listed under the "Stop use and ask a doctor if" section of the DFL within the first 12 weeks of using the study product out of the total population of men in Cohort 1 is presented along with 95% exact two sided Clopper-Pearson confidence interval

Percentage of Men Who Report at Baseline a Symptom or Condition Under the "Ask A Doctor Before Use" Section of the DFL and Initiate Contact With a Doctor Out of the Total Population in Cohort 124 weeks

Percentage of men who reported at baseline a symptom or condition under the "Ask A Doctor Before Use" section of the DFL and initiated contact with a doctor out of the total population of men in Cohort 1 is presented along with 95% exact two sided Clopper-Pearson confidence interval.

Percentage of Men Who Report at Baseline a Symptom or Condition Under the "Ask A Doctor Before Use" Section of the DFL and Initiate Contact With a Doctor Out of the Total Population of Cohort 1 Who Report a Symptom or Condition24 weeks

Percentage of men who reported at baseline a symptom or condition under the "Ask A Doctor Before Use" section of the DFL and initiated contact with a doctor out of the total population of men in Cohort 1 who reported a symptom or condition is presented along with 95% exact two sided Clopper-Pearson confidence interval.

Trial Locations

Locations (38)

Kroger Pharmacy #342

🇺🇸

Cary, North Carolina, United States

Garden Drug

🇺🇸

Fort Lauderdale, Florida, United States

Eagle Pharmacy

🇺🇸

Houston, Texas, United States

Family Plaza Pharmacy

🇺🇸

West Jordan, Utah, United States

Kusler's Compounding Pharmacy

🇺🇸

Snohomish, Washington, United States

Parkway Discount Drugs

🇺🇸

Birmingham, Alabama, United States

Homewood Pharmacy

🇺🇸

Homewood, Alabama, United States

Robert's Discount Pharmacy

🇺🇸

Hoover, Alabama, United States

ACACIA Apothecary and Wellness

🇺🇸

Tucson, Arizona, United States

Pharmacy at the Pig

🇺🇸

McCalla, Alabama, United States

Pinson Discount Drugs

🇺🇸

Pinson, Alabama, United States

Pill Box Pharmacy

🇺🇸

Pembroke Pines, Florida, United States

Parkview Compounding Pharmacy

🇺🇸

Rancho Cucamonga, California, United States

Family Care Pharmacy

🇺🇸

Highland, Illinois, United States

Wynn's Pharmacy Incorporated

🇺🇸

Griffin, Georgia, United States

Goodrich Pharmacy

🇺🇸

Elk River, Minnesota, United States

Cub Pharmacy #1924

🇺🇸

Saint Louis Park, Minnesota, United States

Northfield Pharmacy

🇺🇸

Northfield, Minnesota, United States

Texas Road Pharmacy

🇺🇸

Monroe, New Jersey, United States

Apex Specialty Pharmacy

🇺🇸

Riverside, Missouri, United States

Albers' Specialty Pharmacy

🇺🇸

Kansas City, Missouri, United States

Stevenson Family Pharmacy

🇺🇸

Saint Joseph, Missouri, United States

Countryside Pharmacy

🇺🇸

Savannah, Missouri, United States

Duran Central Pharmacy

🇺🇸

Albuquerque, New Mexico, United States

Charleston Pharmacy, South Charleston

🇺🇸

South Charleston, Ohio, United States

Mountain West Apothecary

🇺🇸

Bountiful, Utah, United States

Maple Mountain Pharmacy

🇺🇸

Mapleton, Utah, United States

T.B. Bond Pharmacy

🇺🇸

Hillsboro, Texas, United States

The Medicine Shoppe

🇺🇸

Ogden, Utah, United States

Rxtra Care

🇺🇸

Seattle, Washington, United States

Kelley-Ross Compounding Pharmacy

🇺🇸

Seattle, Washington, United States

Huff's Drug Store

🇺🇸

Ellijay, Georgia, United States

The Medicine Shoppe and Elsberry Pharmacy

🇺🇸

Elsberry, Missouri, United States

Sam's Regent Pharmacy

🇺🇸

Albuquerque, New Mexico, United States

Sutton Family Pharmacy

🇺🇸

Dalton, Georgia, United States

Total Care Pharmacy

🇺🇸

Burlington, North Carolina, United States

Med Center Compounding Pharmacy & Health Center

🇺🇸

Cleveland, Tennessee, United States

Foothills Compounding Pharmacy

🇺🇸

Enumclaw, Washington, United States

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