Early Debridement Within 24 Hours After Surgery Compared Routine Debridement (24 Hours Later) for Wound Healing of Abdominal Incision
Overview
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 480
- Locations
- 1
- Primary Endpoint
- healing time, d (day)
Overview
Brief Summary
Wound healing after surgery is a complex procedure. Liquefaction of the fat and necrosis of inactivated tissue, as well as blood clots are always accumulated mostly within 24 hours after surgery. As such, early debridement within 24 hours after surgery might improve the healing of the wounds. This study is designed to compare the impact of early debridement of the wound versus regular dressing (24 hours later) on the wound healing. 100 patients will be included in this study, and divided into 2 groups randomly. Then, the healing of the wound, stitch removal time, incidence of incision complications will be compared between the two groups.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •the patient with major abdominal incision.
Exclusion Criteria
- •Pregnant woman
- •Patient with diabetes
- •Patient with a history of cardiovascular disease, including coronary heart disease and stroke.
- •Severe lung diseases such as COPD and asthma
- •Patients undergoing emergent surgery or infectious surgery
- •Patients with surgical site infection or abdominal abscess
- •No autonomy, inability or unwillingness to participate in follow-up
Outcomes
Primary Outcomes
healing time, d (day)
Time Frame: From date of surgery to the date of stitches off (up to 1 month)
since the ending of surgery to stitches off.
Secondary Outcomes
- incidence of incision complications(From the date of surgery to stitches off (up to 1 month))