Early Debridement Within 24 Hours After Surgery Compared Routine Debridement (24 Hours Later) for Wound Healing of Abdominal Incision
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 480
- 试验地点
- 1
- 主要终点
- healing time, d (day)
研究概览
简要总结
Wound healing after surgery is a complex procedure. Liquefaction of the fat and necrosis of inactivated tissue, as well as blood clots are always accumulated mostly within 24 hours after surgery. As such, early debridement within 24 hours after surgery might improve the healing of the wounds. This study is designed to compare the impact of early debridement of the wound versus regular dressing (24 hours later) on the wound healing. 100 patients will be included in this study, and divided into 2 groups randomly. Then, the healing of the wound, stitch removal time, incidence of incision complications will be compared between the two groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •the patient with major abdominal incision.
排除标准
- •Pregnant woman
- •Patient with diabetes
- •Patient with a history of cardiovascular disease, including coronary heart disease and stroke.
- •Severe lung diseases such as COPD and asthma
- •Patients undergoing emergent surgery or infectious surgery
- •Patients with surgical site infection or abdominal abscess
- •No autonomy, inability or unwillingness to participate in follow-up
结局指标
主要结局
healing time, d (day)
时间窗: From date of surgery to the date of stitches off (up to 1 month)
since the ending of surgery to stitches off.
次要结局
- incidence of incision complications(From the date of surgery to stitches off (up to 1 month))