Early Debridement Within 24 Hours After Surgery for Wound Healing of Abdominal Incision

Not Applicable

Completed

• Conditions: Surgical Wound
• Interventions: Behavioral: Debridement Within 24 Hours After Surgery

• Registration Number: NCT03798041
• Lead Sponsor: First Affiliated Hospital Xi'an Jiaotong University

Brief Summary

Wound healing after surgery is a complex procedure. Liquefaction of the fat and necrosis of inactivated tissue, as well as blood clots are always accumulated mostly within 24 hours after surgery. As such, early debridement within 24 hours after surgery might improve the healing of the wounds. This study is designed to compare the impact of early debridement of the wound versus regular dressing (24 hours later) on the wound healing. 100 patients will be included in this study, and divided into 2 groups randomly. Then, the healing of the wound, stitch removal time, incidence of incision complications will be compared between the two groups.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-01-01
• Study First Submitted QC: 2019-01-06
• Study First Posted: 2019-01-09
• Study Start: 2019-02-01
• Status Verified: 2021-03
• Primary Completion: 2021-03-16
• Study Completion: 2021-03-16
• Last Update Submitted: 2021-12-07
• Last Update Posted: 2021-12-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 480

Inclusion Criteria

• the patient with major abdominal incision.

Exclusion Criteria

• Pregnant woman
• Patient with diabetes
• Patient with a history of cardiovascular disease, including coronary heart disease and stroke.
• Severe lung diseases such as COPD and asthma
• Patients undergoing emergent surgery or infectious surgery
• Patients with surgical site infection or abdominal abscess
• No autonomy, inability or unwillingness to participate in follow-up

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Debridement group	Debridement Within 24 Hours After Surgery	The subjects in this group will be debrided within 24 hours after surgery.

Primary Outcome Measures

Name	Time	Method
healing time, d (day)	From date of surgery to the date of stitches off (up to 1 month)	since the ending of surgery to stitches off.

Secondary Outcome Measures

Name	Time	Method
incidence of incision complications	From the date of surgery to stitches off (up to 1 month)	The incision complications include infection, dehiscence, fat liquefaction, etc.

Trial Locations

Locations (1)

The First Affiliated Hospital of Xi'an Jiaotong University; 🇨🇳 Xi'an, Shaanxi, China