Effect of extraperitoneal instillation of 0.5% bupivacaine for postoperative analgesia in laparoscopic hernioplasty: a randomized controlled trial

Phase 4

Recruiting

• Conditions: Patients that receive an operation laparoscopic totally extraperitoneal hernioplasty.; inguinal hernia, bupivacaine, laparoscopic

• Registration Number: TCTR20231021003
• Lead Sponsor: Research department, Faculty of medicine, Siriraj hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-10-21
• Last Update Posted: 19 August 2024
• Study Completion: 2025-03-31

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. 18 years of age or more
2. A person who receives a surgery, laparoscopic totally extraperitoneal hernioplasty at Siriraj Hospital from October 1, 2023 to March 31, 2025.
3. Participants can listen and understand Thai language and can give a consent for research.
4. The person who receives a single operation at the time of surgery
5. The patient has a ASA (American socity anesthesiologyist) physical status I - III.

Exclusion Criteria

1. Incarcerated inguinal hernia or strangulated inguinal hernia
2. Giant inguinal hernia(larger than half of thigh)
3. History of drug allergy that use in research : paracetamol, morphine, fentanyl, and etoricoxib
4. Restrictions in using research-related drugs include; moderate to severe kidney disease, a history of cardiovascular disease, congestive heart failure, history of coronary artery bypass graft, asthma, cirrhosis
5. Unable to communicate or to tell the degree of pain.
6. Recurrent inguinal hernia
7. Bilateral inguinal hernia that surgery both sides in the same operation.
8. Weight less than 35 kgs at time of admission

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain score 1 hr Numeric rating scale

Secondary Outcome Measures

Name	Time	Method
Pain score 30 min, 90 min, 120 min, 4 hrs, 6hrs, 8 hrs, 10 hrs, 12 hrs, 24 hrs Numeric rating scale,Time to first analgesia When pain score upto 4 points Time after surgery,Time to first sit, stand and walk when patient start to sit, stand, and walk time,Morphine use in 24 hrs 24 hours Morphine milligram equivalent,Length of hospital stay when patient ready to discharge Hours