Induction chemotherapy followed by radiotherapy in locally advanced head and neck cancers.
Phase 2
- Conditions
- Health Condition 1: C01- Malignant neoplasm of base of tongue
- Registration Number
- CTRI/2023/08/056851
- Lead Sponsor
- Department of Radiotherapy and Radiation Medicine,
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1)Histologically proven oropharynx, larynx, hypopharynx cancer
2)Stage III-IV
3)Squamous cell carcinoma
4) ECOG 0-1
Exclusion Criteria
1) Previously treated Head and Neck Malignancy
2) Pregnant Lactating Females
3) Received chemotherapy and radiotherapy earlier
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1)loco regional control <br/ ><br>2) Acute toxicity <br/ ><br>3) quality of LifeTimepoint: 6 months
- Secondary Outcome Measures
Name Time Method 1) overall survival <br/ ><br>2) Disease free survival <br/ ><br>3)late toxictyTimepoint: 6 months