Risk Factors for COVID-19 Mortality: a Prospective Observational Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- COVID-19 Virus Infection
- Sponsor
- Teodoro Marcianò
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- Mortality rate
- Status
- Terminated
- Last Updated
- 4 years ago
Overview
Brief Summary
COVID-19 pandemic has deeply burdened hospitals all over the world. A two-stage disease has been hypothesized due to quick worsening of clinical status after 7-10 days from the beginning of first symptoms, generally flu-like symptoms. Predicting clinical worsening could help to address major efforts towards higher risk patients.
During the last year most observational studies, generally retrospective, has been conducted, identifying some risk factors such as age, obesity, male gender, cardiovascular disease, COPD, diabetes etc.
The study goal is to collect systematically a variegate amount of clinical, biometric, laboratory and radiological data from patients admitted to the Emergency Medicine Ward of Piacenza Hospital (Italy), in order to prospectively analyze what characteristics are associated to higher risk of mortality.
Investigators
Teodoro Marcianò
Doctor of Medicine, Emergency Medicine Specialist
Azienda Unità Sanitaria Locale di Piacenza
Eligibility Criteria
Inclusion Criteria
- •Admission to the Emergency Medicine Ward from the Emergency Department of Piacenza Hospital (Italy)
- •Confirmed COVID-19 diagnosis through molecular test obtained from nasal-pharyngeal swabs in the Emergency Department
- •Age above 18
Exclusion Criteria
- •inability to obtain an informed consent due to neurological conditions.
- •patient's refusal to sign the informed consent
- •inability of researchers to recruit the patient in the first 24 hours from the admission.
Outcomes
Primary Outcomes
Mortality rate
Time Frame: 28 days after admission
Number of patients who die for any cause in the first 28 days after admission
Secondary Outcomes
- Need of invasive ventilation(15 days after admission)