Risk Factors for COVID-19 Mortality

Terminated

• Conditions: COVID-19 Virus Infection; Population at Risk; Acute Respiratory Distress Syndrome

• Registration Number: NCT04786808
• Lead Sponsor: Teodoro Marcianò

Brief Summary

COVID-19 pandemic has deeply burdened hospitals all over the world. A two-stage disease has been hypothesized due to quick worsening of clinical status after 7-10 days from the beginning of first symptoms, generally flu-like symptoms. Predicting clinical worsening could help to address major efforts towards higher risk patients.

During the last year most observational studies, generally retrospective, has been conducted, identifying some risk factors such as age, obesity, male gender, cardiovascular disease, COPD, diabetes etc.

The study goal is to collect systematically a variegate amount of clinical, biometric, laboratory and radiological data from patients admitted to the Emergency Medicine Ward of Piacenza Hospital (Italy), in order to prospectively analyze what characteristics are associated to higher risk of mortality.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-01-15
• Study First Submitted: 2021-03-05
• Study First Submitted QC: 2021-03-05
• Study First Posted: 2021-03-08
• Status Verified: 2021-11
• Primary Completion: 2021-11-07
• Study Completion: 2021-11-07
• Last Update Submitted: 2021-11-07
• Last Update Posted: 2021-11-15

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Admission to the Emergency Medicine Ward from the Emergency Department of Piacenza Hospital (Italy)
• Confirmed COVID-19 diagnosis through molecular test obtained from nasal-pharyngeal swabs in the Emergency Department
• Age above 18

Exclusion Criteria

• inability to obtain an informed consent due to neurological conditions.
• patient's refusal to sign the informed consent
• inability of researchers to recruit the patient in the first 24 hours from the admission.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mortality rate	28 days after admission	Number of patients who die for any cause in the first 28 days after admission

Secondary Outcome Measures

Name	Time	Method
Need of invasive ventilation	15 days after admission	Number of patients who need invasive ventilation in the first 15 days after admission

Trial Locations

Locations (1)

Azienda USL di Piacenza; 🇮🇹 Piacenza, Emilia-Romagna, Italy