Evaluation of the Effect of Cerebrospinal Fluid Drainage on Optic Nerve Sheath Diameter in Patients Installed External Ventricular Drainage Catheter Due to Intracranial Pathology in the Intensive Care Unit
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 44
- 试验地点
- 2
- 主要终点
- Intracranial Pressure-1 (ICP-1)
研究概览
简要总结
Determination of high intracranial pressure (ICP) is necessary for the treatment of patients with raised ICP to improve long-term neurological outcomes. Ultrasonographic optic nerve sheath diameter (ONSD) measurement is a noninvasive, easily performed and cost effective technique for detecting high ICP.
详细描述
ICP measurements via ventricular catheters provide CSF drainage and ICP reduction. The normal ICP value is less than 15 mmHg in adults. In the literature the correlation of ONSD and invasive ICP measurements were determined. The aim of study is to evaluate the correlation of ONSD and direct ICP measurements and to determine cut off ONSD value to detect ICP ≥15 mmHg.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18-80 aged patients
- •With an external ventricular drainage catheter due to intracranial pathology
排除标准
- •Under the age of 18
- •Orbital tumors
- •Graves' disease
- •Exophthalmos
- •Sarcoidosis
- •Optic neuropathy
- •Meningitis
- •Ocular trauma
- •Lung diseases
结局指标
主要结局
Intracranial Pressure-1 (ICP-1)
时间窗: baseline time
Measurement of intracranial pressure before cerebrospinal fluid (CSF) drainage
Optic Nerve Sheath Diameter-1 (ONSD-1)
时间窗: baseline time
Measurement of optic nerve sheath diameter before cerebrospinal fluid drainage
次要结局
- Intracranial Pressure-2 (ICP-2)(2 minutes after CSF drainage)
- Optic Nerve Sheath Diameter-2 (ONSD-2)(2 minutes after CSF drainage)
研究者
Gülşah ORAK
Medical Doctor-Anesthesiology and Reanimation
Istanbul University - Cerrahpasa