Evaluation of the Effect of Cerebrospinal Fluid Drainage on Optic Nerve Sheath Diameter in Patients Installed External Ventricular Drainage Catheter Due to Intracranial Pathology in the Intensive Care Unit
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- ICP (Intracranial Pressure) Increase
- Sponsor
- Istanbul University - Cerrahpasa (IUC)
- Enrollment
- 44
- Locations
- 1
- Primary Endpoint
- Intracranial Pressure-1 (ICP-1)
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Determination of high intracranial pressure (ICP) is necessary for the treatment of patients with raised ICP to improve long-term neurological outcomes. Ultrasonographic optic nerve sheath diameter (ONSD) measurement is a noninvasive, easily performed and cost effective technique for detecting high ICP.
Detailed Description
ICP measurements via ventricular catheters provide CSF drainage and ICP reduction. The normal ICP value is less than 15 mmHg in adults. In the literature the correlation of ONSD and invasive ICP measurements were determined. The aim of study is to evaluate the correlation of ONSD and direct ICP measurements and to determine cut off ONSD value to detect ICP ≥15 mmHg.
Investigators
Gülşah ORAK
Medical Doctor-Anesthesiology and Reanimation
Istanbul University - Cerrahpasa (IUC)
Eligibility Criteria
Inclusion Criteria
- •18-80 aged patients
- •With an external ventricular drainage catheter due to intracranial pathology
Exclusion Criteria
- •Under the age of 18
- •Orbital tumors
- •Graves' disease
- •Exophthalmos
- •Sarcoidosis
- •Optic neuropathy
- •Meningitis
- •Ocular trauma
- •Lung diseases
Outcomes
Primary Outcomes
Intracranial Pressure-1 (ICP-1)
Time Frame: baseline time
Measurement of intracranial pressure before cerebrospinal fluid (CSF) drainage
Optic Nerve Sheath Diameter-1 (ONSD-1)
Time Frame: baseline time
Measurement of optic nerve sheath diameter before cerebrospinal fluid drainage
Secondary Outcomes
- Intracranial Pressure-2 (ICP-2)(2 minutes after CSF drainage)
- Optic Nerve Sheath Diameter-2 (ONSD-2)(2 minutes after CSF drainage)