A Retrospective Clinical Registry of Peripheral Nerve Block: Current Practice and Complications

Instituto de Investigación Sanitaria Aragón1 site in 1 country13,816 target enrollmentJanuary 1, 2011

Overview

Brief Summary

Locorregional anaesthesia have been increased its role in different kind of surgeries, alone or combined with general anesthesia. Due to ultrasound, peripheral nerve blocks have been increased their importance in locoregional anaesthesia. They provide excellent intraoperative and postoperative analgesia, decreasing the need for intravenous opioids which increase postoperative nausea and vomiting which may prolong hospital stay.

The primary study objective is to analyze retrospectively the use of peripheral nerve blocks in the current practice of a specialized regional anaesthesia division.

This is an observational, retrospective and unicenter study. 1346 patients scheduled for the surgery needed a peripheral nerve block were enrolled.

Detailed Description

Locorregional anaesthesia have been increased its role in different kind of surgeries, alone or combined with general anesthesia. Due to ultrasound, peripheral nerve blocks have been increased their importance in locoregional anaesthesia. They provide excellent intraoperative and postoperative analgesia, decreasing the need for intravenous opioids which increase postoperative nausea and vomiting which may prolong hospital stay. However, peripheral nerve blocks may be associated with postoperative complications, especially neurological ones. Classically, interscalene brachial plexus block produced a 100% incidence of phrenic nerve paralysis with resultant pulmonary compromise. Little literature has published a following of complications. The primary study objective is to analyze retrospectively the use of peripheral nerve blocks in the current practice of a specialized regional anaesthesia division. The secondary objectives are assessed the patients characteristics of our sample, local anaesthetic dose used, the peripheral nerve block operator, the nerve location technique, the surgery and the complication rate after peripheral nerve block. This is an observational, retrospective and unicenter study. 1346 patients scheduled for the surgery needed a peripheral nerve block were enrolled.

Registry

clinicaltrials.gov

Start Date

January 1, 2011

End Date

November 30, 2019

Last Updated

3 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Instituto de Investigación Sanitaria Aragón

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Every patient who needs a peripheral nerve block performed by Anestesia Department.

Exclusion Criteria

•Patient refusal of peripheral nerve block.
•Known allergy to amide local anaesthetic drugs
•Absolute contraindications to perform a peripheral nerve block as coagulopathy, active infection at the block site or severe respiratory background.

Outcomes

Primary Outcomes

Peripheral nerve block

Time Frame: During procedure

This primary outcome is the type of peripheral nerve block performed

Incidence and frequency of Serious Adverse Events (SAE)

Time Frame: From performing the peripheral nerve block to 1-year follow-up

This primary outcome is the incidence, frequency and severity of Serious Adverse Events (SAE) as assessed by CTCAE v4.0 after peripheral nerve block.

Secondary Outcomes

Incidence and frequency of Postoperative neurological complications (PONC)(From performing the peripheral nerve block to 1-year follow-up)
Local anesthetic dose used in peripheral nerve block(During procedure)
Local anesthetic used in peripheral nerve block(During procedure)
Peripheral nerve block operator(During procedure)
Local anesthetic volume used in peripheral nerve block(During procedure)
Nerve location technique used in peripheral nerve block(During procedure)