Hereditary hearing impairment in the Netherlands: elucidation of genetic causes, and clinical characterization.

Recruiting

• Conditions: 10013995; hereditary deafness; hereditary hearing impairment

• Registration Number: NL-OMON47077
• Lead Sponsor: KNO

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 2050

Inclusion Criteria

patients with hearing impairment in whom common non-genetic causes for hearing impairment are excluded.

Exclusion Criteria

patients with age-related hearing impairment

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1, pathologic genetic variants that are known to or are likely to be causative<br /><br>for hearing impairment. 2, genotype-phenotype correlations for at least part of<br /><br>the genetic subtypes leading to improved counselling. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>A strategy for DNA-diagnostics for hearing impairment in the Dutch population.</p><br>